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- Table of Contents
Facts about Glutathione S-transferase A4.
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Human | |
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Gene Name: | GSTA4 |
Uniprot: | O15217 |
Entrez: | 2941 |
Belongs to: |
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GST superfamily |
DKFZp686D21185; EC 2.5.1.18; glutathione S-alkyltransferase A4; glutathione S-aralkyltransferase A4; glutathione S-aryltransferase A4; glutathione S-transferase A4; Glutathione S-transferase A4-4; glutathione S-transferase alpha 4; glutathione transferase A4-4; GST class-alpha member 4; GSTA4-4; GTA4; S-(hydroxyalkyl)glutathione lyase A4
Mass (kDA):
25.704 kDA
Human | |
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Location: | 6p12.2 |
Sequence: | 6; NC_000006.12 (52977952..52995332, complement) |
Expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver.
Cytoplasm.
PMID: 9461507 by Hubatsch I., et al. Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation.
PMID: 9480897 by Board P.G.; Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4.