GSPT1 Antibodies

AND GSPT1 ELISA kits, GSPT1 Proteins

Many biological assays use antibodies to detect GSPT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GSPT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GSPT1 antibodies...

We validate the specificity of these antibodies to GSPT1 by testing them on tissues known to express GSPT1 positively and negatively. Browse below to find the GSPT1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GSPT1 Infographic by Boster Bio

All GSPT1 Products

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Anti-eRF3a GSPT1 Antibody

6 Q&As

Human, Mouse, Rat

$399
Cat # A07761
100μl

Anti-eRF3a (D128) GSPT1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07761-1
100ul

GSPT1 Overview

Facts about Eukaryotic peptide chain release factor GTP-binding subunit ERF3A.

GSPT1 3D structure. Source: alphafold

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1)

Involved in translation termination in response to the termination codons UAA, UAG and UGA. Stimulates the action of ERF1.

Involved in regulation of mammalian cell growth. Part of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

Gene Information

Human
Gene Name:	GSPT1
Uniprot:	P15170
Entrez:	2935

Family

Belongs to:

TRAFAC class translation factor GTPase superfamily

Alternative Names

ERF3A; eRF3aFLJ38048; ETF3A; eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Eukaryotic peptide chain release factor subunit 3a; FLJ39067; G1 to S phase transition 1,551G9.2; G1 to S phase transition protein 1 homolog; GST1

Molecular Weight

Mass (kDA):
55.756 kDA

Genomic Context


Human

Location:	16p13.13
Sequence:	16; NC_000016.10 (11868128..11916654, complement)

Diseases

Malignant Neoplasms
Neoplasms
Stomach Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach
Tumor Progression
Carcinoma
Mammary Neoplasms
Liver Diseases
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Non-neoplastic Disorder

Hepatitis C, Chronic
Trinucleotide Repeat Expansion
Hepatitis B
Endometrial Polyp
Malignant Neoplasm Of Liver
Carcinogenesis
Leukemia, Myelocytic, Acute

Interacting Proteins

ETF1
PABPC1
UPF1

Pathways

Translation
Cell Cycle
S Phase
Localization
Methylation
Cell Proliferation
Translational Termination
Gluconeogenesis
Chromosome Segregation
Cell Division
Cytoskeleton Organization

Reverse Transcription
Protein Folding
Regulation Of Cell Proliferation
Cell Growth
Chromatin Remodeling

PTMs

Methylation
Phosphorylation

Cleavage
Ubiquitination

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GSPT1

References

PMID: 2511002 by Hoshino S., et al. A human homologue of the yeast GST1 gene codes for a GTP-binding protein and is expressed in a proliferation-dependent manner in mammalian cells.

PMID: 19417104 by Yamashita A., et al. SMG-8 and SMG-9, two novel subunits of the SMG-1 complex, regulate remodeling of the mRNA surveillance complex during nonsense-mediated mRNA decay.