G-rich sequence factor 1 Antibodies

AND GRSF1 ELISA kits, G-rich sequence factor 1 Proteins

Many biological assays use antibodies to detect G-rich sequence factor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with G-rich sequence factor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop G-rich sequence factor 1 antibodies...

We validate the specificity of these antibodies to G-rich sequence factor 1 by testing them on tissues known to express GRSF1 positively and negatively. Browse below to find the GRSF1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRSF1 Infographic by Boster Bio

All GRSF1 Products

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Product

Figures

Specificity

Applications

Price

Anti-GRSF1 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07576-2
100 μg/vial

Anti-GRSF1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, ICC, WB

$370
Cat # M07576
100 μl/vial

Anti-GRSF1 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M07576-1
100 μl/vial

GRSF1 (NM_001098477) Human Over-expression Lysate

Human

$628
Cat # LS002926
100 µg

GRSF1 Overview

Facts about G-rich sequence factor 1.

GRSF1 3D structure. Source: alphafold

G-rich sequence factor 1 (GRSF1)

Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element.

Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. .

Gene Information

Human
Gene Name:	GRSF1
Uniprot:	Q12849
Entrez:	2926

Family

Belongs to:

No superfamily

Alternative Names

FLJ13125; G-rich RNA sequence binding factor 1; G-rich sequence factor 1; GRSF-1

Molecular Weight

Mass (kDA):
53.126 kDA

Genomic Context


Human

Location:	4q13.3
Sequence:	4; NC_000004.12 (70815783..70843274, complement)

Subcellular Localizations

[Isoform 1]: Mitochondrion matrix. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.; [Isoform 2]: Cytoplasm.

Diseases

Influenza
Virus Diseases
Immunologic Deficiency Syndromes
Impacted Tooth
Epithelial Metaplasia
Neoplasms
Hiv Infections
Developmental Delay (disorder)

Oligospermia
Tissue Adhesions

Interacting Proteins

PSMD10

Pathways

Translation
Brain Development
Cell Adhesion
Gastrulation
Stem Cell Differentiation
Cell Development
Mesoderm Formation
Localization
Spermatogenesis
Rna Splicing
Paraxial Mesoderm Formation
Germ Cell Development

Viral Transcription
Cell Cycle
Cell Differentiation
Mrna Processing
Rna Processing
Rna Interference

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRSF1

References

PMID: 8036161 by Qian Z., et al. GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element.

PMID: 23473033 by Antonicka H., et al. The mitochondrial RNA-binding protein GRSF1 localizes to RNA granules and is required for posttranscriptional mitochondrial gene expression.