Gastrin-releasing peptide Antibodies

AND GRP ELISA kits, Gastrin-releasing peptide Proteins

Many biological assays use antibodies to detect Gastrin-releasing peptide, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gastrin-releasing peptide in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gastrin-releasing peptide antibodies...

We validate the specificity of these antibodies to Gastrin-releasing peptide by testing them on tissues known to express GRP positively and negatively. Browse below to find the GRP antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GRP Infographic by Boster Bio

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Gastrin Releasing Peptide (GRP) (NM_002091) Human Over-expression Lysate

Human

$628
Cat # LS002922
100 µg

GRP Overview

Facts about Gastrin-releasing peptide.

GRP 3D structure. Source: alphafold

Gastrin-releasing peptide (GRP)

Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimulation and to the transmission of itch signals in the spinal cord that encourage scratching behaviour.

Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory.

Gene Information

Human
Gene Name:	GRP
Uniprot:	P07492
Entrez:	2922

Family

Belongs to:

bombesin/neuromedin-B/ranatensin family

Alternative Names

BN; Bombesin; Gastrinreleasing Peptide; Gastrin-releasing Peptide; GRP; GRP10; GRP-10; neuromedin C; pre-progastrin releasing peptide; preproGRP; proGRP

Molecular Weight

Mass (kDA):
16.213 kDA

Genomic Context


Human

Location:	18q21.32
Sequence:	18; NC_000018.10 (59219188..59230771)

Subcellular Localizations

Secreted. Cytoplasmic vesicle, secretory vesicle lumen.

Diseases

Malignant Neoplasms
Neoplasms
Carcinoma
Malignant Neoplasm Of Lung
Small Cell Carcinoma Of Lung
Lung Neoplasms
Malignant Neoplasm Of Prostate
Prostatic Neoplasms
Nervousness
Adenocarcinoma
Neoplasm Metastasis
Pituitary Diseases

Malignant Neoplasm Of Breast
Malignant Paraganglionic Neoplasm
Endoplasmic Reticulum Stress
Malignant Tumor Of Colon
Mammary Neoplasms
Physiological Stress
Tissue Adhesions

Pathways

Secretion
Localization
Cell Proliferation
Acid Secretion
Cell Death
Cell Growth
Innervation
Pathogenesis
Gastric Acid Secretion
Transport
Insulin Secretion
Cell Cycle
Angiogenesis

Regeneration
Lung Development
Hormone Secretion
Excretion
Cell Differentiation
Translation
Somatostatin Secretion

PTMs

Phosphorylation
Cleavage
Amidation
Glycosylation
Reduction
Iodination
Biotinylation
Methylation
Oxidation
Acetylation

Sulphation
Dephosphorylation
Nitrosylation
Hydroxylation
Ribosylation
Deamidation
Ubiquitination
Gamma-carboxylation
Geranylgeranylation
Deglycosylation

Research Areas

GPCR
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GRP

References

PMID: 3001723 by Spindel E.R., et al. Two prohormones for gastrin-releasing peptide are encoded by two mRNAs differing by 19 nucleotides.

PMID: 3211139 by Lebacq-Verheyden A.-M., et al. Posttranslational processing of endogenous and of baculovirus- expressed human gastrin-releasing peptide precursor.