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- Table of Contents
Facts about Metabotropic glutamate receptor 7.
Signaling inhibits adenylate cyclase activity. .
Human | |
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Gene Name: | GRM7 |
Uniprot: | Q14831 |
Entrez: | 2917 |
Belongs to: |
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G-protein coupled receptor 3 family |
FLJ40498; glutamate receptor, metabotropic 7; GPRC1G; GRM7; metabotropic glutamate receptor 7; MGLU7; mGluR7; MGLUR7GPRC1GGLUR7
Mass (kDA):
102.251 kDA
Human | |
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Location: | 3p26.1 |
Sequence: | 3; NC_000003.12 (6861115..7743038) |
Expressed in many areas of the brain, especially in the cerebral cortex, hippocampus, and cerebellum. Expression of GRM7 isoforms in non-neuronal tissues appears to be restricted to isoform 3 and isoform 4.
Cell membrane; Multi-pass membrane protein.
PMID: 8840028 by Makoff A., et al. Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS.
PMID: 9144652 by Flor P.J., et al. A novel splice variant of a metabotropic glutamate receptor, human mGluR7b.