GPT Antibodies

Alanine aminotransferase 1 (GPT)

Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in mobile nitrogen metabolism and also in liver gluconeogenesis beginning with precursors transported from skeletal muscles (By similarity).

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Gene Information

Human
Gene Name:	GPT
Uniprot:	P24298
Entrez:	2875

Family

Belongs to:
class-I pyridoxal-phosphate-dependent aminotransferase family

Alternative Names

AAT1alanine aminotransferase 1; ALT1; ALT1EC 2.6.1.2; Glutamate pyruvate transaminase 1; glutamic-alanine transaminase 1; Glutamic--alanine transaminase 1; glutamic-pyruvate transaminase (alanine aminotransferase); Glutamic--pyruvic transaminase 1; GPT1GPT 1

Molecular Weight

Mass (kDA):
54.637 kDA

Genomic Context

Human
Location:	8q24.3
Sequence:	8; NC_000008.11 (144502217..144507174)

Tissue Specificity

Liver, kidney, heart, and skeletal muscles. Expressed at moderate levels in the adipose tissue.

Subcellular Localizations

Cytoplasm.

Diseases

• Infective Disorder
• Liver Diseases
• Hepatitis
• Bacterial Infections
• Drug-induced Liver Injury
• Liver Damage
• Injury To Liver
• Hepatotoxicity
• Pneumonia
• Malignant Neoplasms
• Neoplasms
• Urinary Tract Infection
• Diarrhea

• Liver Cirrhosis
• Respiratory Tract Infections
• Carcinoma
• Exanthema
• Eosinophilia
• Tonsillitis
• Bronchitis

Pathways

• Excretion
• Pathogenesis
• Coagulation
• Regeneration
• Secretion
• Dna Repair
• Transport
• Localization
• Cell Proliferation
• Glycosylation
• Conjugation
• Aging
• Methylation

• Immune Response
• Cell Death
• Hypersensitivity
• Liver Regeneration
• Dna Methylation
• Drug Resistance
• Lactation

PTMs

• Glycosylation
• Methylation
• Oxidation
• Reduction
• Nitration
• Cleavage
• Amination
• Phosphorylation
• Demethylation

• Acetylation
• Deamination
• Hydroxylation
• Ribosylation
• Formylation
• Phosphorothioation
• Decarboxylation
• Ubiquitination
• Iodination

• Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPT

Boster Bio - Best Uses Of The GPT Marker

You've come the right place If you're looking to learn more about Steven Boster or the company which he established. This article is going to focus on Steven's background, High-affinity primary antibodies and the company's current products. I hope you find the information you're searching for to be useful and useful. Here are some tips to select the most effective antibodies for your research.

History of the company

Developing a standardized ELISA platform is a crucial element of the Boster family history, which began in 1993. Boster's first products included ELISA kits for IHC, a type of immunohistochemistry. Boster was China's largest supplier of antibodies in the late 1990s and early 2000s. The company also created trade secrets for high-sensitivity ELISA kit kits. Today, the company employs this platform, which has been described as "the next generation of ELISA kits."

High-affinity primary antibodies

When using flow cytometry, researchers utilize monoclonal or polyclonal antibodies in order to detect a variety of proteins such as cancer cells and DNA. Boster Bio provides highly specific antibodies that are suitable for this type of research. Many of these antibodies have received an array of references, and are produced by an ISO-9001 certified company.

Boster Bio's range of antibodies comprises more than 12,000 antibodies which have been validated for WB and ELISA. The collection of antibodies is designed to be utilized in ELISA and WB, and is used for a variety research applications that include neuroscience. Boster Bio products come with a 100% quality guarantee that includes an exclusive High-Affinity Primary Guarantee. They are among the top in class in terms of affinity and sensitivity, and you can buy these with confidence knowing that you'll get what pay for.

The h5E12-L230G antibody was developed using the hybridoma procedure to create a murine-specific mAb against the hPCSK9. The antibody, m5E12L230G was able to restore PCSK9-induced LDLR degradation and blocked LDL uptake in HepG2 cells. By using a scFv-based format, the m5E12L230G antigen was more easily humanized than the full-length version. The scFv proteins can be obtained from an E. coli expression system, which is fast growing and inexpensive.

The h5E12 antibody has a high affinity for the m5E12. The m5E12ScFv antibody was created by the grafting of murine CDRs onto human antigen chains. Human antibodies are identified by an accession number in GenBank and were later back-mutated by replacing the conserved residue N97, with a more human version.

Recombinant antigens have excellent stability. The antibody produced in these facilities is not affected by cell-line drift. This process also lets antibodies achieve their highest specificity for antigens. The antibodies are also protected from degradation during transport or storage. If you're considering boster Bio products for your research, contact Sanbio today. You'll be grateful you did.

Current products

The GPT marker gene is located on chromosome 2 at TOPBP1 locus. It can be used for positive and negative testing with MPA or 6-TX. It has a gus gene that enhances all major test functions. The GPT-9900 series has an advanced measurement capability, sweep function, and displays test results. This GPT marker gene was created using genomic PCR products.