This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
1 Q&As
Facts about G-protein coupled receptor 37-like 1.
However, other studies have shown that prosaposin doesn't increase action (PubMed:27072655, PubMed:28688853). It's been suggested that GPR37L1 is a constitutively active receptor that signals through the guanine nucleotide-binding protein G(s) subunit alpha (PubMed:27072655).
Human | |
---|---|
Gene Name: | GPR37L1 |
Uniprot: | O60883 |
Entrez: | 9283 |
Belongs to: |
---|
G-protein coupled receptor 1 family |
endothelin B receptor-like protein 2; ET(B)R-LP-2; ETBRLP2; ETBR-LP-2; ETBR-LP-2endothelin type b receptor-like protein 2; G protein-coupled receptor 37 like 1; GPR37L1; G-protein coupled receptor 37 like 1; G-protein coupled receptor 37-like 1
Mass (kDA):
52.771 kDA
Human | |
---|---|
Location: | 1q32.1 |
Sequence: | 1; NC_000001.11 (202118669..202133592) |
Expressed in primary cortical astrocytes (at protein level) (PubMed:23690594). Expressed in the central nervous system (PubMed:9539149).
Cell membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein. Associates with the basal membrane of Bergmann glia cell primary cilia.
PMID: 9539149 by Valdenaire O., et al. A new family of orphan G protein-coupled receptors predominantly expressed in the brain.
PMID: 23690594 by Meyer R.C., et al. GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.