GPR3 Antibodies

AND GPR3 ELISA kits, GPR3 Proteins

Many biological assays use antibodies to detect GPR3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPR3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPR3 antibodies...

We validate the specificity of these antibodies to GPR3 by testing them on tissues known to express GPR3 positively and negatively. Browse below to find the GPR3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GPR3 Infographic by Boster Bio

All GPR3 Products

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Anti-G-protein coupled receptor 3 GPR3 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A07114
0.1 mg

GPR3 (NM_005281) Human Over-expression Lysate

Human

$628
Cat # LS002827
100 µg

GPR3 Overview

Facts about G-protein coupled receptor 3.

GPR3 3D structure. Source: alphafold

G-protein coupled receptor 3 (GPR3)

Orphan receptor using constitutive G(s) signaling activity that trigger cyclic AMP. Has a possible role in modulating a variety of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons and neurite outgrowth (By similarity).

Maintains also meiotic arrest in oocytes (By similarity). .

Gene Information

Human
Gene Name:	GPR3
Uniprot:	P46089
Entrez:	2827

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

ACCA; G protein-coupled receptor 3; GPR3

Molecular Weight

Mass (kDA):
35.01 kDA

Genomic Context


Human

Location:	1p36.11
Sequence:	1; NC_000001.11 (27392622..27395814)

Tissue Specificity

Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Alzheimer's Disease
Premature Menopause
Pituitary Diseases
Nervousness
Turner Syndrome
Ovarian Failure, Premature
Malignant Neoplasms
Pertussis
Female Infertility
Sclerosis
Malnutrition
Stenosis
Feeling Despair

Spinal Cord Injuries
Insulinoma
Peripheral Nerve Injuries
Neurodegenerative Disorders
Malignant Neoplasm Of Breast
Dementia
Infertility

Pathways

Prophase
Meiosis
Oocyte Maturation
Localization
Ovulation
Aging
Cell Cycle
Oogenesis
Rna Interference
Muscle Cell Proliferation
Fertilization
Hypersensitivity
Inflammatory Response

Sensitization
Chemotaxis
Cell Motility
Receptor-mediated Endocytosis
Ovarian Follicle Development
Smooth Muscle Cell Proliferation
Cell Proliferation

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GPR3

References

PMID: 8530049 by Song Z.-H., et al. Molecular cloning and chromosomal localization of human genes encoding three closely related G protein-coupled receptors.

PMID: 7698767 by Iismaa T.P., et al. Isolation and chromosomal localization of a novel human G-protein- coupled receptor (GPR3) expressed predominantly in the central nervous system.