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- Table of Contents
Facts about Aspartate aminotransferase, mitochondrial.
Significant for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
Human | |
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Gene Name: | GOT2 |
Uniprot: | P00505 |
Entrez: | 2806 |
Belongs to: |
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class-I pyridoxal-phosphate-dependent aminotransferase family |
aspartate aminotransferase, mitochondrial; EC 2.6.1; EC 2.6.1.1; FABP-1; FABPpm; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase2); KAT4; KATIV; kynurenine aminotransferase IV; mAspAT; mitAAT; Plasma membrane-associated fatty acid-binding protein; Transaminase A
Mass (kDA):
47.518 kDA
Human | |
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Location: | 16q21 |
Sequence: | 16; NC_000016.10 (58707131..58734316, complement) |
Mitochondrion matrix. Cell membrane. Exposure to alcohol promotes translocation to the cell membrane.
PMID: 3207426 by Pol S., et al. Nucleotide sequence and tissue distribution of the human mitochondrial aspartate aminotransferase mRNA.
PMID: 4052435 by Martini F., et al. The primary structure of mitochondrial aspartate aminotransferase from human heart.
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