GNRHR Antibodies

AND GNRHR ELISA kits, GNRHR Proteins

Many biological assays use antibodies to detect GNRHR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GNRHR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GNRHR antibodies...

We validate the specificity of these antibodies to GNRHR by testing them on tissues known to express GNRHR positively and negatively. Browse below to find the GNRHR antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GNRHR Infographic by Boster Bio

All GNRHR Products

Product

Figures

Specificity

Applications

Price

Anti-GnRH-R Antibody

1 Citations

Human, Mouse

ELISA, IF, WB

$380
Cat # A01442
100ul

GNRHR (NM_000406) Human Over-expression Lysate

Human

$628
Cat # LS002798
100 µg

GNRHR Overview

Facts about Gonadotropin-releasing hormone receptor.

GNRHR 3D structure. Source: alphafold

Gonadotropin-releasing hormone receptor (GNRHR)

Receptor for gonadotropin releasing hormone (GnRH) which mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle- stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol- calcium second messenger system.

Isoform 2 may serve as an inhibitor of GnRH-R signaling. .

Gene Information

Human
Gene Name:	GNRHR
Uniprot:	P30968
Entrez:	2798

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

GnRH receptor; GnRHR; GnRH-R; GNRHR1; gonadotropin-releasing hormone (type 1) receptor 1; gonadotropin-releasing hormone receptor; GRHR; HH7; leutinizing-releasing hormone receptor; LHRHR; LHRHRleutinizing hormone releasing horomone receptor; LRHR; luliberin receptor; Luliberin; type I GnRH receptor

Molecular Weight

Mass (kDA):
37.731 kDA

Genomic Context


Human

Location:	4q13.2
Sequence:	4; NC_000004.12 (67737118..67754388, complement)

Tissue Specificity

Pituitary, ovary, testis, breast and prostate but not in liver and spleen.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Pituitary Diseases
Hypogonadism
Hypogonadotropic Hypogonadism
Malignant Neoplasms
Idiopathic Hypogonadotropic Hypogonadism
Kallmann Syndrome
Neoplasms
Ovarian Neoplasm
Anosmia
Malignant Neoplasm Of Ovary
Infertility
Delayed Puberty
Mammary Neoplasms

Carcinoma
Malignant Neoplasm Of Breast
Amenorrhea
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Endometrial Polyp
Cryptorchidism

Pathways

Secretion
Ovulation
Cell Proliferation
Localization
Gonadotropin Secretion
Translation
Pathogenesis
Fertilization
Hormone Secretion
Receptor Internalization
Cell Growth
Cell Adhesion
Spermatogenesis

Progesterone Secretion
Estrus
Thelarche
Cell Death
Proestrus
Protein Folding
Hatching

PTMs

Phosphorylation
Reduction
Palmitoylation
Glycosylation

Acetylation
Ribosylation
Myristoylation
Iodination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNRHR

References

PMID: 1333190 by Kakar S.S., et al. Cloning, sequencing, and expression of human gonadotropin releasing hormone (GnRH) receptor.

PMID: 8386108 by Chi L., et al. Cloning and characterization of the human GnRH receptor.

1 Publications of Boster GNRHR Antibodies & ELISA Kits

PubMed ID: -, Steven G. Waldrop,Garrett P. Smith,Stephen M. Boyle,Nammalwar Sriranganathan,Bru...

*More publications can be found for each product on its corresponding product page