Granulysin Antibodies

AND GNLY ELISA kits, Granulysin Proteins

Many biological assays use antibodies to detect Granulysin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Granulysin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Granulysin antibodies...

We validate the specificity of these antibodies to Granulysin by testing them on tissues known to express GNLY positively and negatively. Browse below to find the GNLY antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GNLY Infographic by Boster Bio

All GNLY Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Human Granulysin ELISA Kit PicoKine®

2 Citations 8 Q&As

Human

ELISA

$750
Cat # EK1280
96 wells/kit, with removable strips.

GNLY Granulysin Human Recombinant Protein

Human

$250
Cat # PROTP22749
2ug, 10ug, 1mg

Human Granulysin PicoKine® Quick ELISA Kit

1 Q&As

Human

ELISA

$499
Cat # FEK1280
96 wells/kit, with removable strips.

Anti-Granulysin GNLY Antibody

Human

ELISA, WB

$380
Cat # A01836
100ul

GNLY (NM_006433) Human Over-expression Lysate

Human

$628
Cat # LS010578
100 µg

GNLY Overview

Facts about Granulysin.

GNLY 3D structure. Source: alphafold

Granulysin (GNLY)

Antimicrobial protein which kills intracellular pathogens. Active against a broad array of microbes, such as Gram-positive and Gram-negative bacteria, fungi, and parasites.

Kills Mycobacterium tuberculosis. .

Gene Information

Human
Gene Name:	GNLY
Uniprot:	P22749
Entrez:	10578

Family

Belongs to:

No superfamily

Alternative Names

D2S69Elymphocyte-activation gene 2; GNLY; Granulysin; LAG2; LAG-2; Lymphokine LAG-2; Lymphokine; NKG5; NKG5519; Protein NKG5; TLA519; TLA519T-cell activation protein 519; T-lymphocyte activation gene 519

Molecular Weight

Mass (kDA):
16.374 kDA

Genomic Context


Human

Location:	2p11.2
Sequence:	2; NC_000002.12 (85694294..85698854)

Tissue Specificity

Expressed in natural killer and T-cells.

Subcellular Localizations

Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.

Diseases

Neoplasms
Tuberculosis
Malignant Neoplasms
Infective Disorder
Bacterial Infections
Hiv Infections
Inflammation
Tuberculosis, Pulmonary
Immunologic Deficiency Syndromes
Cell Invasion
Carcinoma
Stevens-johnson Syndrome

Infection By Cryptococcus Neoformans
Communicable Diseases
Lymphoma
Leprosy
Hepatitis B
Hepatitis
Mycobacterium Infections

Pathways

Immune Response
Exocytosis
Cell Death
Pathogenesis
Cell Activation
Secretion
Localization
T Cell Activation
Cytolysis
Killer Activity
Chemotaxis
Cytokine Production
Granulysin Production

Cell Adhesion
Transport
Hypersensitivity
Inflammatory Response
Translation
Innate Immune Response
Cell Proliferation

PTMs

Cleavage

Phosphorylation

Reduction

Research Areas

Adaptive Immunity
Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNLY

References

PMID: 2434598 by Jongstra J., et al. The isolation and sequence of a novel gene from a human functional T cell line.

PMID: 2212946 by Yabe T., et al. A cDNA clone expressed in natural killer and T cells that likely encodes a secreted protein.

2 Publications of Boster Granulysin Antibodies & ELISA Kits

PubMed ID: PMID:31933981, Increased granulysin in the peripheral blood and tissues of patients with oral l...
PubMed ID: 10.1111/and.13066, Assessment of seminal granulysin in infertile men with varicocele

*More publications can be found for each product on its corresponding product page