Granulysin Antibodies

Granulysin (GNLY)

Antimicrobial protein which kills intracellular pathogens. Active against a broad array of microbes, such as Gram-positive and Gram-negative bacteria, fungi, and parasites.

Kills Mycobacterium tuberculosis. .

Gene Information

Human
Gene Name:	GNLY
Uniprot:	P22749
Entrez:	10578

Family

Belongs to:
No superfamily

Alternative Names

D2S69Elymphocyte-activation gene 2; GNLY; Granulysin; LAG2; LAG-2; Lymphokine LAG-2; Lymphokine; NKG5; NKG5519; Protein NKG5; TLA519; TLA519T-cell activation protein 519; T-lymphocyte activation gene 519

Molecular Weight

Mass (kDA):
16.374 kDA

Genomic Context

Human
Location:	2p11.2
Sequence:	2; NC_000002.12 (85694294..85698854)

Tissue Specificity

Expressed in natural killer and T-cells.

Subcellular Localizations

Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.

Diseases

• Neoplasms
• Tuberculosis
• Malignant Neoplasms
• Infective Disorder
• Bacterial Infections
• Hiv Infections
• Inflammation
• Tuberculosis, Pulmonary
• Immunologic Deficiency Syndromes
• Cell Invasion
• Carcinoma
• Stevens-johnson Syndrome

• Infection By Cryptococcus Neoformans
• Communicable Diseases
• Lymphoma
• Leprosy
• Hepatitis B
• Hepatitis
• Mycobacterium Infections

Pathways

• Immune Response
• Exocytosis
• Cell Death
• Pathogenesis
• Cell Activation
• Secretion
• Localization
• T Cell Activation
• Cytolysis
• Killer Activity
• Chemotaxis
• Cytokine Production
• Granulysin Production

• Cell Adhesion
• Transport
• Hypersensitivity
• Inflammatory Response
• Translation
• Innate Immune Response
• Cell Proliferation

PTMs

• Cleavage

• Phosphorylation

• Reduction

Research Areas

• Adaptive Immunity
• Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GNLY

Boster Bio - Best Uses Of The GNLY Marker

What is Boster Bio's "GNLY Marker"? If you're searching for a genetic marker or gene you've come the right spot. This section will discuss its advantages and ways to utilize it. Continue reading to learn more. Here are some of its most notable features. Also, be sure to check out Boster Bio's comprehensive technical resources blog posts, blogs, and information on diseases. Boster Bio's high-quality lysis buffers ensure good results and minimize cross-linking strength.

Boster Bio's GNLY Marker

Scientists across the globe can make use of the GNLY Marker to detect the nutrient in samples from any species. Scientists can submit their results to receive credit for product or specific species-specific applications. The GNLY Marker is applicable for use in all kinds of studies from agriculture to medical research. Visit Boster Bio's website for more information about the GNLY Marker. Read on to learn more.

GNLY Marker is a GNLY Marker

The GNLY sequence of mRNA has little similarity to published sequences. The GNLY gene is present in leukocytes, spleens and thymus in humans. Its expression is low in the heart, kidney and liver. This protein could be used as a diagnostic tool for chronic myelogenous leukemia. The protein is found on more than 80 percent of all B-cells which are the cause of inflammatory diseases.

GNLY Marker is an expression of a gene

Boster Bio's online guide to optimization will help you gain a better understanding of how to maximize the use of GNLY Marker. These guides will help inform your choices and assist you in improving your experiments. In addition to technical guides, Boster offers blogs and specific information for diseases. These guides feature high-quality lysis buffers that minimize cross-linking. These guides are precise and precise, so you can trust them to deliver the best results.

GNLY Marker is a protein

GNLY Marker is a human-derived polypeptide chain that has amino acids of 159 and an additional double His tag. Its molecular mass is 18.1 kDa. Boster Bio uses mouse and rabbit as models to develop antibodies to this protein. GNLY Marker is a key component of sarcomere structure, connecting Z-disks and sarcomeres and enhancing the strength of movement.