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- Table of Contents
Facts about GMP reductase 1.
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP.
It works in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides..
Human | |
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Gene Name: | GMPR |
Uniprot: | P36959 |
Entrez: | 2766 |
Belongs to: |
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IMPDH/GMPR family |
EC 1.7.1.7; GMPR1GMP reductase 1; guanine monophosphate reductase; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1; guanosine monophosphate reductase
Mass (kDA):
37.419 kDA
Human | |
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Location: | 6p22.3 |
Sequence: | 6; NC_000006.12 (16238587..16295549) |
PMID: 2758468 by Kanno H., et al. Two structural genes on different chromosomes are required for encoding the major subunit of human red cell glucose-6-phosphate dehydrogenase.
PMID: 1661705 by Kondoh T., et al. Genomic structure and expression of human guanosine monophosphate reductase.