GLS Antibodies

AND GLS ELISA kits, GLS Proteins

Many biological assays use antibodies to detect GLS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GLS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GLS antibodies...

We validate the specificity of these antibodies to GLS by testing them on tissues known to express GLS positively and negatively. Browse below to find the GLS antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GLS Infographic by Boster Bio

All GLS Products

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Product

Figures

Specificity

Applications

Price

Anti-Glutaminase GLS Rabbit Monoclonal Antibody

6 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M01272
100 μl

Anti-GLS Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A01272
100ul

Anti-Glutaminase GLS Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01272-1
100ul

Anti-Glutaminase/GLS Antibody Picoband®

+11

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A01272-2
100 μg/vial

Anti-GLS Antibody (C-Term)

Human, Mouse

$299
Cat # M01272-1
50 µl

Anti-Glutaminase/GLS Antibody Picoband® (monoclonal, 9G6)

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M01272-2
100 μg/vial

Anti-Glutaminase/GLS Antibody Picoband® (monoclonal, 3G13)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01272-3
100 μg/vial

Glutaminase (GLS) (NM_014905) Human Over-expression Lysate

Human

$628
Cat # LS002744
100 µg

GLS Overview

Facts about Glutaminase kidney isoform, mitochondrial.

GLS 3D structure. Source: alphafold

Glutaminase kidney isoform, mitochondrial (GLS)

Catalyzes the initial reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in keeping acid-base homeostasis.

Regulates the amount of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity.

Gene Information

Human
Gene Name:	GLS
Uniprot:	O94925
Entrez:	2744

Family

Belongs to:

glutaminase family

Alternative Names

AAD20; EC 3.5.1.2; GLS; GLS1DKFZp686O15119; glutaminase C; glutaminase kidney isoform, mitochondrial; Glutaminase; glutaminase, phosphate-activated; K-Glutaminase; KIAA0838FLJ10358; L-Glutamine Amidohydrolase

Molecular Weight

Mass (kDA):
73.461 kDA

Genomic Context


Human

Location:	2q32.2
Sequence:	2; NC_000002.12 (190880821..190965552)

Tissue Specificity

Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle.

Subcellular Localizations

[Isoform 1]: Mitochondrion. Cytoplasm, cytosol. The 74-kDa cytosolic precursor is translocated into the mitochondria and processed via a 72-kDa intermediate to yield the mature 68- and 65-kDa subunits.; [Isoform 3]: Mitochondrion.; [Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix. Produced by the proteolytic processing of the 74-kDa cytosolic precursor.; [Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix. Produced by the proteolytic processing of the 74-kDa cytosolic precursor.