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- Table of Contents
Facts about Glutaredoxin-related protein 5, mitochondrial.
Required for normal iron homeostasis. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1 (PubMed:20364084).
Human | |
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Gene Name: | GLRX5 |
Uniprot: | Q86SX6 |
Entrez: | 51218 |
Belongs to: |
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glutaredoxin family |
C14orf87chromosome 14 open reading frame 87; FLB4739; glutaredoxin 5 homolog (S. cerevisiae); glutaredoxin 5 homolog; glutaredoxin 5; glutaredoxin-related protein 5, mitochondrial; GRX5; MGC14129; Monothiol glutaredoxin-5; PR01238; PRO1238
Mass (kDA):
16.628 kDA
Human | |
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Location: | 14q32.13 |
Sequence: | 14; NC_000014.9 (95535050..95544714) |
Mitochondrion matrix.
PMID: 16110529 by Wingert R.A., et al. Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.
PMID: 17485548 by Camaschella C., et al. The human counterpart of zebrafish shiraz shows sideroblastic-like microcytic anemia and iron overload.