Glycerol kinase Antibodies

Glycerol kinase (GK)

Key enzyme in the regulation of glycerol uptake and metabolism. .

Gene Information

Human
Gene Name:	GK
Uniprot:	P32189
Entrez:	2710

Family

Belongs to:
FGGY kinase family

Alternative Names

ATP:glycerol 3-phosphotransferase; EC 2.7.1.30; GK; GK1; GKD; glpK; Glycerokinase; Glycerol Kinase

Molecular Weight

Mass (kDA):
61.245 kDA

Genomic Context

Human
Location:	Xp21.2
Sequence:	X; NC_000023.11 (30653348..30731462)

Tissue Specificity

Highly expressed in the liver, kidney and testis. Isoform 2 and isoform 3 are expressed specifically in testis and fetal liver, but not in the adult liver.

Subcellular Localizations

Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. In sperm and fetal tissues, the majority of the enzyme is bound to mitochondria, but in adult tissues, such as liver found in the cytoplasm.

Diseases

• Diabetes Mellitus
• Diabetes Mellitus, Non-insulin-dependent
• Hyperglycemia
• Diabetes Mellitus, Experimental
• Insulin Resistance
• Obesity
• Neoplasms
• Impaired Glucose Tolerance
• Diabetes Mellitus, Insulin-dependent
• Hyperinsulinism
• Hypoglycemia
• Insulin Sensitivity
• Inflammation

• Pituitary Diseases
• Brain Neoplasms
• Kidney Diseases
• Diabetic Nephropathy
• Deficiency Of Glycerol Kinase
• Hypertensive Disease
• Fibrosis

Interacting Proteins

• NR4A1

Pathways

• Secretion
• Insulin Secretion
• Glucose Homeostasis
• Pathogenesis
• Glycolysis
• Transport
• Localization
• Gluconeogenesis
• Glucose Transport
• Exocytosis
• Cell Death
• Aging
• Cell Proliferation

• Membrane Depolarization
• Excretion
• Angiogenesis
• Regeneration
• Cell Growth
• Membrane Hyperpolarization
• Translation

PTMs

• Phosphorylation
• Oxidation
• Cleavage
• Glycosylation
• Dephosphorylation
• Reduction
• Acetylation
• Nitration
• Carboxylation

• Nitrosylation
• Methylation
• Deacetylation
• Sumoylation
• Hydroxylation
• Acylation
• Ubiquitination
• Palmitoylation
• Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GK

Best Uses Of The GK Marker

Boster is a company which produces monoclonal and high-affinity primary antibodies. Boster produces the anti-CD68 monoclonal antibodies. Scientists from all over the world are encouraged to submit their findings using this product. They will be able to be awarded credits for their work. The product also provides multiple options for submitting samples. This product is open to all Boster scientists regardless of background.

Boster's high-affinity primary antibody

Boster Bio has a wide variety of high-affinity primary antibodies that are ideal for use in ELISA and immunohistochemistry. The reagents of the company are based on a proprietary platform that improves ELISA sensitivity to the picogram level. The antibodies are rigorously tested in various assays and applications. Products from Boster Bio have received more than 29,000 citations. They are available for both ELISA as well as WB applications. Boster bio products include a range of WB and ELISA assay kits. The company's antibodies cover different research fields including neuroscience. Boster's Quality Guarantee guarantees that the kits or reagents will perform as stated on their labels.

Boster manufactures its products in-house, which guarantees high quality and efficiency. Additionally, the company maintains ISO 9001 certification. Boster's primary antibodies as as ELISA kits are of the highest quality. These products are supported by a commitment to customer service. You can order them on the website of the company or call them at 1-800-426-9472. A representative will be in touch with you shortly.

The company provides a broad range of high-affinity primary antibodies for various research topics. The high specificity and affinity of these antibodies make them a valuable option for immunoblotting and ELISA. The antibodies from Boster's lab are ideal for many immunological applications, including flow cytometry and immunohistochemistry. These primary antibodies are versatile and a great tool for researchers who want to determine a protein target.

Non-specific materials can be easily removed due to the high affinity of their primary antibodies. This makes the method an effective instrument to measure specific analytes in crude preparations. However it requires careful selection of primary antibodies with high affinity for the best results. Ask the manufacturer about the quality and safety of the high-affinity antibodies you require.

High-affinity primary antibodies have high affinity and are not affected by heat. They are particularly resistant to temperatures above 60 degrees Celsius, which makes them valuable for immunohistochemistry. For immunohistochemistry, these antibodies differ in their affinity for antigens. Monoclonal antibody can have an affinity constant of between 10-6 and 10.9. The strongest noncovalent bond found in nature is the biotin-avidin bond.

Boster's anti-TLR4 antibody was purchased from Boster, Wuhan, China. The staining was quantified by measuring the optical density of the region of interest (IOD).

The report on the World Research Antibodies Market provides information on major organizations, regions, and types as well as the end-users. It also includes cost breakdowns and growth rates year-over-year, and other factors driving the market. The complete report will give you more understanding and insight into the market. It provides a comprehensive overview of the market worldwide for Research Antibodies.

Monoclonal antibodies are made from the VHH gene followed by His-tag peptide's encoding sequence. Recombinant phage-clones were utilized to produce the peptides. Five phage-clones positive for antibodies were utilized to express antibodies. Each clone included the VHH gene as well as His tag peptide's encoded sequence. Figure 3 below illustrates the results.

It is a monoclonal anti-CD68 antigen.

The monoclonal antibody anti-CD68 is a highly specific, multi-functional tool for the analysis of cells that express CD68. In the human body, CD68 is expressed mainly on macrophages, which includes monocytes and osteoclasts. However the protein is present in many tissue types, including the skin and synovial membrane. The antibodies are available for research purposes in both human and mouse versions.

Boster Bio's anti-CD68 monoclonal antibodies for mice react with CD68 which is the marker protein for macrophages. The monoclonal antibody is able to react with Rabbit, Human Primate, and Human and Non-Human Primate. It is utilized in Immunohistochemistry and in studies of Immunofluorescence.

Anti-CD68 antibody recognizes 110kDa glycoprotein which is highly expressed in monocytes and microphages. It also stains plasmacytoid T cells that are supposed to be derived from macrophages or monocytes. It is a method to distinguish between Myelomonocytic tumors and diseases that share similar features.

The company was founded in 1993 by a world-famous histologist, Steven Xia, specializes in the creation of high-specific, high-affinity antibodies. It was founded in 1993. Boster Bio has spent two decades perfecting its techniques and technologies. Boster Bio's antibodies' high-affinity, specificity, and other properties have been referenced in more than 29,000 scientific articles. Boster offers a Boster Quality Guarantee and continually expands its product range.

CD68 is a 110 kD transmembrane glycoprotein. It is part of the LAMP family that includes LAMP-1, the LAMP-2 protein, brain and dendritic cell-associated (BAD)-LAMP, and CD208. The CD68 protein is composed of one LAMP domain, and Mucin-like domain. It is an integral membrane protein of type I that binds specific organ lecins and is dispersed on murine and human cell lines.