Gja10 Antibodies

AND Gja10 ELISA kits, Gja10 Proteins

Many biological assays use antibodies to detect Gja10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gja10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gja10 antibodies...

We validate the specificity of these antibodies to Gja10 by testing them on tissues known to express Gja10 positively and negatively. Browse below to find the Gja10 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Gja10 Infographic by Boster Bio

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GJA10 (NM_032602) Human Over-expression Lysate

Human

$960
Cat # LS084694
100 µg

Gja10 Overview

Facts about Gap junction alpha-10 protein.

Gap junction alpha-10 protein (Gja10)

1 gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling between horizontal cells of the retina.

May play a role in the regulation of horizontal cell patterning. .

Gene Information

Mouse
Gene Name:	Gja10
Uniprot:	Q9WUS4
Entrez:	14610

Family

Belongs to:

connexin family

Alternative Names

Connexin 62; connexin-62; Cx62; CX62gap junction alpha-10 protein; gap junction protein, alpha 10, 62kDa; GJA10; RP11-63K6.6

Molecular Weight

Mass (kDA):
57.127 kDA

Genomic Context


Mouse

Location:	4 A5\|4 14.25 cM
Sequence:	4;

Tissue Specificity

Low levels were detected in skin, heart, kidney, testis, ovary, intestine. Expression not detected in brain, sciatic nerve or liver. According to PubMed:15147297 expression is detected only in horizontal cells in the inner nuclear layer of the retina and not in other neurons of the central nervous system or tissues. Detected in the outer plexiform layer of the retina (at protein level).

Diseases

Fracture Of First Cervical Vertebra
Congenital Abnormality
Retinal Degeneration
Neurodegenerative Disorders
Ataxia
Diphtheria
Diabetes Mellitus
Disorder Of Eye
Diabetes Mellitus, Experimental

Diabetes Mellitus, Insulin-dependent
Ataxia, Spinocerebellar
Retinal Diseases

Pathways

Blastocyst Formation
Signal Transmission
Blastocyst Development
Oocyte Growth
Localization
Cell Maturation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gja10

References

PMID: 10329667 by Manthey D., et al. Molecular cloning and functional expression of the mouse gap junction gene connexin-57 in human HeLa cells.

PMID: 15147297 by Hombach S., et al. Functional expression of connexin57 in horizontal cells of the mouse retina.