GIGYF2 Antibodies

AND GIGYF2 ELISA kits, GIGYF2 Proteins

Many biological assays use antibodies to detect GIGYF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GIGYF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GIGYF2 antibodies...

We validate the specificity of these antibodies to GIGYF2 by testing them on tissues known to express GIGYF2 positively and negatively. Browse below to find the GIGYF2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GIGYF2 Infographic by Boster Bio

All GIGYF2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GIGYF2 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04303
100ul

Anti-PERQ2 GIGYF2 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A04303-1
100ul

Anti-GIGYF2 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04303-2
100 μg/vial

GIGYF2 (NM_001103146) Human Over-expression Lysate

Human

$960
Cat # LS026058
100 µg

GIGYF2 Overview

Facts about GRB10-interacting GYF protein 2.

GIGYF2 3D structure. Source: alphafold

GRB10-interacting GYF protein 2 (GIGYF2)

Key component of the 4EHP-GYF2 complicated, a multiprotein complex that functions as a repressor of translation initiation (PubMed:22751931). In 4EHP-GYF2 the complex, functions as a factor that bridges EIF4E2 into ZFP36/TTP, linking translation repression with mRNA decay (By similarity).

May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling, including IGF1 and insulin receptors (PubMed:12771153). .

Gene Information

Human
Gene Name:	GIGYF2
Uniprot:	Q6Y7W6
Entrez:	26058

Family

Belongs to:

GIGYF family

Alternative Names

DKFZp686J17223; FLJ23368; GRB10 interacting GYF protein 2; GRB10-interacting GYF protein 2; GYF domain containing 2; GYF2; KIAA0642DKFZp686I15154; PARK11; Parkinson disease (autosomal recessive, early onset) 11; PERQ amino acid rich, with GYF domain 2; PERQ amino acid rich, with GYF domain 3; PERQ amino acid-rich with GYF domain-containing protein 2; PERQ2; PERQ3; TNRC15; trinucleotide repeat containing 15; Trinucleotide repeat-containing gene 15 protein

Molecular Weight

Mass (kDA):
150.07 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (232697331..232860605)

Diseases

Parkinson Disease
Secondary Parkinson Disease
Mammary Neoplasms
Nerve Degeneration
Essential Tremor
Malignant Neoplasms
Resting Tremor
Liver Carcinoma
Malignant Neoplasm Of Breast
Neurodegenerative Disorders
Nervous System Disorder

Carcinogenesis
Bradykinesia
Neoplasms
Senile Plaques
Movement Disorders

Pathways

Pathogenesis
Transport
Histone Deacetylation
Secretory Pathway
Cell Proliferation
Hepatocyte Differentiation
Neuron Differentiation
Mrna Splicing
Translation

Cell Differentiation
Cell Growth
Mrna Processing
Chromatin Remodeling

PTMs

Phosphorylation

Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GIGYF2

References

PMID: 12771153 by Giovannone B., et al. Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling.

PMID: 19279319 by Nichols W.C., et al. Variation in GIGYF2 is not associated with Parkinson disease.