Gfra4 Antibodies

AND Gfra4 ELISA kits, Gfra4 Proteins

Many biological assays use antibodies to detect Gfra4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Gfra4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Gfra4 antibodies...

We validate the specificity of these antibodies to Gfra4 by testing them on tissues known to express Gfra4 positively and negatively. Browse below to find the Gfra4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Gfra4 Infographic by Boster Bio

All Gfra4 Products

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Product

Figures

Specificity

Applications

Price

Anti-GF alpha-4 GFRA4 Antibody

Human

ELISA, WB

$380
Cat # A13441
100ul

Persephin receptor (GFRA4) (NM_022139) Human Over-expression Lysate

Human

$628
Cat # LS064096
100 µg

Gfra4 Overview

Facts about GDNF family receptor alpha-4.

GDNF family receptor alpha-4 (Gfra4)

Receptor for persephin.
Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

May be important in C-cell development and, in the postnatal development of the adrenal medulla. .

Gene Information

Mouse
Gene Name:	Gfra4
Uniprot:	Q9JJT2
Entrez:	14588

Family

Belongs to:

GDNFR family

Alternative Names

GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF R alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha4; GFR alpha-4; GFR receptor alpha 4; GFRA4; GFRa-4; GFR-alpha-4; Persephin receptor

Molecular Weight

Mass (kDA):
27.99 kDA

Genomic Context


Mouse

Location:	2 F1\|2 63.26 cM
Sequence:	2;

Tissue Specificity

Expressed in many tissues including adrenal medulla, brain neurons, with highest levels in the cerebral cortex and hippocampus. Moderate levels found in the gut circular muscle and myenteric ganglia as well as in other peripheral ganglia, including the sensory dorsal root and trigeminal as well as superior cervical and sympathetic chain ganglia. Isoform a1, isoform a2, isoform b1 and isoform b2 are exclusively found in the thyroid, parthyroid and pituitary glands.

Diseases

Endocrine Gland Neoplasms
Neoplasms
Multiple Endocrine Neoplasia Type 2a
Multiple Endocrine Neoplasia
Malignant Neoplasms
Nervousness
Neoplastic Syndromes, Hereditary
Hirschsprung Disease
Disease Of Adrenal Medulla
Neurodegenerative Disorders
Carcinoma
Dysplasia
Asthma

Pituitary Diseases
Dysequilibrium Syndrome
Neuroblastoma
Medullary Carcinoma Of Thyroid
Nerve Degeneration
Multiple Endocrine Neoplasia Type 2b
Schizophrenia

Pathways

Cell Development
Pathogenesis
Spermatogenesis
Secretion

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Gfra4

References

PMID: 10860579 by Lindahl M., et al. Expression and alternative splicing of mouse Gfra4 suggest roles in endocrine cell development.