GDF11 Antibodies

AND GDF11 ELISA kits, GDF11 Proteins

Many biological assays use antibodies to detect GDF11, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GDF11 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GDF11 antibodies...

We validate the specificity of these antibodies to GDF11 by testing them on tissues known to express GDF11 positively and negatively. Browse below to find the GDF11 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GDF11 Infographic by Boster Bio

All GDF11 Products

Product

Figures

Specificity

Applications

Price

Anti-BMP11 GDF11 Rabbit Monoclonal Antibody

4 Q&As

Human, Rat

IF, IHC, ICC, WB

$370
Cat # M02355
100 μl

Human GDF-11/BMP-11 Recombinant Protein

SDS-PAGE, Denatured

$265
Cat # PROTO95390
Starting from 20ug

Anti-GDF11 Antibody (N-term)

Human, Mouse

IHC-P, WB

$298
Cat # A02355
80 µl

GDF11 Overview

Facts about Growth/differentiation factor 11.

GDF11 3D structure. Source: alphafold

Growth/differentiation factor 11 (GDF11)

Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. May play crucial roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern (By similarity).

Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 resulting in the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634). .

Gene Information

Human
Gene Name:	GDF11
Uniprot:	O95390
Entrez:	10220

Family

Belongs to:

TGF-beta family

Alternative Names

GDF-11/GDF-8

Molecular Weight

Mass (kDA):
45.091 kDA

Genomic Context


Human

Location:	12q13.2
Sequence:	12; NC_000012.12 (55743122..55757264)

Subcellular Localizations

Secreted.

PTMs

Cleavage on pair of basic residues

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GDF11

References

PMID: 10075854 by Gamer L.W., et al. A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos.

PMID: 10391213 by McPherron A.C., et al. Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11.