Formin-binding protein 1 Antibodies

AND Fnbp1 ELISA kits, Formin-binding protein 1 Proteins

Many biological assays use antibodies to detect Formin-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Formin-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Formin-binding protein 1 antibodies...

We validate the specificity of these antibodies to Formin-binding protein 1 by testing them on tissues known to express Fnbp1 positively and negatively. Browse below to find the Fnbp1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Fnbp1 Infographic by Boster Bio

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FBP17 (FNBP1) (NM_015033) Human Over-expression Lysate

Human

$628
Cat # LS023048
100 µg

Fnbp1 Overview

Facts about Formin-binding protein 1.

Formin-binding protein 1 (Fnbp1)

Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late phase of clathrin-mediated endocytosis. Binds to lipids like phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules.

Also enhances actin polymerization through the recruitment of WASL/N-WASP, which subsequently activates the Arp2/3 complex. Actin polymerization may foster the fission of membrane tubules to form endocytic vesicles.

Gene Information

Mouse
Gene Name:	Fnbp1
Uniprot:	Q80TY0
Entrez:	14269

Family

Belongs to:

FNBP1 family

Alternative Names

FBP17KIAA0554Formin-binding protein 17; formin binding protein 1; formin-binding protein 1; hFBP17; MGC126804

Molecular Weight

Mass (kDA):
71.344 kDA

Genomic Context


Mouse

Location:	2\|2 B
Sequence:	2;

Tissue Specificity

Expressed in brain and testis.

Diseases

Neoplasms
Malignant Neoplasms
Leukemia
Wiskott-aldrich Syndrome
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Chondrosarcoma
Cell Invasion
Retinoblastoma
Neoplasm Metastasis
Oncogene Activation Process
Moderate Mental Retardation

Mutation, Out-of-frame
Melanoma
X-linked Combined Immunodeficiency Diseases
Carcinoma
Immunologic Deficiency Syndromes
Del(12p13)
Myeloid Leukemia

Pathways

Endocytosis
Membrane Tubulation
Localization
Cell Division
Membrane Invagination
Clathrin-mediated Endocytosis
Cell Migration
Cell Motility
Actin Nucleation
Transport
Actin Cytoskeleton Reorganization
Gene Silencing
Dna Methylation

Methylation
Chemotaxis
Phagocytosis
Regulation Of Cell Shape
Limb Morphogenesis
Cell Cycle
Protein Folding

PTMs

Phosphorylation
Demethylation

Reduction
Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Fnbp1

References

PMID: 15252009 by Kamioka Y., et al. A novel dynamin-associating molecule, formin-binding protein 17, induces tubular membrane invaginations and participates in endocytosis.