Frizzled-1 Antibodies

Frizzled-1 (FZD1)

Activated by WNT3A, WNT3, WNT1 and to a lesser extent WNT2, but apparently not by WNT4, WNT5A, WNT5B, WNT6, WNT7A or WNT7B (PubMed:10557084). Contradictory results demonstrating activation by WNT7B have been described for mouse (By similarity).

Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:10557084). The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes (PubMed:10557084).

Gene Information

Human
Gene Name:	FZD1
Uniprot:	Q9UP38
Entrez:	8321

Family

Belongs to:
G-protein coupled receptor Fz/Smo family

Alternative Names

DKFZp564G072; FLJ95923; frizzled family receptor 1; frizzled homolog 1; frizzled, Drosophila, homolog of, 1; Frizzled1; Frizzled-1; fz-1; FZD1; fzE1; hFz1; seven transmembrane spanning receptor; Wnt receptor

Molecular Weight

Mass (kDA):
71.158 kDA

Genomic Context

Human
Location:	7q21.13
Sequence:	7; NC_000007.14 (91264433..91271326)

Tissue Specificity

Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

• Malignant Neoplasms
• Neoplasms
• Carcinoma
• Cell Transformation, Neoplastic
• Malignant Neoplasm Of Breast
• Mammary Neoplasms
• Carcinogenesis
• Malignant Paraganglionic Neoplasm
• Malignant Neoplasm Of Stomach
• Malignant Tumor Of Colon
• Pertussis
• Intestinal Diseases
• Ulcer

• Congenital Abnormality
• Tissue Adhesions
• Hyperplasia
• Stomach Neoplasms
• Neoplasm Metastasis
• Inflammatory Bowel Diseases
• Adenomatous Polyposis Coli

Pathways

• Cell Proliferation
• Localization
• Cell Fate Determination
• Rna Interference
• Regeneration
• Pathogenesis
• Osteoblast Differentiation
• Mating
• Ear Development
• Programmed Cell Death
• Neurogenesis
• Inner Ear Development
• Cell Cycle

• Wound Healing
• Endoderm Formation
• Cell Death
• Cell Adhesion
• Clathrin-mediated Endocytosis
• Hair Follicle Development
• Cell Activation

PTMs

• Phosphorylation

• Glycosylation

• Palmitoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FZD1

Boster Bio Anti-FZD1 Marker

If you're looking for a high-affinity primary antibody for the FZD1 marker, you've come to the right place. Boster provides antibodies that are highly cited and validated for use in Western Blotting, Immunohistochemistry, and ELISA experiments. The FZD1 marker is an important part of the NF-kappa-B family.

Boster Bio Anti-KHDRBS2 Antibody

Boster Bio Anti-KHDRBS2-FZD1-KHDRBS2 Immunoglobulin is a polyclonal monoclonal antibody that reacts with Human and mouse cells. The antibody is tested on several platforms for its high affinity and specificity. The Boster Bio Anti-KHDRBS2-FZD1-KHDRBS2 Immunoglobulin has been published in scientific journals for more than 25 years.

Boster Bio Anti-Bax (S4) Antibody

This boster bio Anti-Bax antibody has been tested for a variety of applications, including IP and IHC. The antibody reacted with Human, Mouse, and Rat. Researchers worldwide can use this antibody for a wide variety of applications. Scientists can submit results for species-specific studies, species-specific applications, and more. They can also submit results to obtain product credits.

Boster Bio Anti-FZD1 Antibody

Using Boster Bio Anti-FZD1 antibody is an excellent way to perform immunohistochemistry and Western blotting experiments. This antibody is high-affinity and has been used extensively by the research community for over 25 years. Its naming rule is the same as for other antibodies of its class, making it a perfect choice for immunohistochemistry and Western blotting studies.