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Forkhead box protein K1 Antibodies
AND Foxk1 ELISA kits, Forkhead box protein K1 Proteins
Many biological assays use antibodies to detect Forkhead box protein K1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Forkhead box protein K1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Forkhead box protein K1 antibodies...
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Foxk1 Infographic by Boster Bio
All Foxk1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA
$480
Cat # EKC1766
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1766
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A07015-2
100 μg/vial
Cat # A07015-2
100 μg/vial
Foxk1 Overview
Facts about Forkhead box protein K1.
Forkhead box protein K1 (Foxk1)
Important regulatory factor of the myogenic progenitor cell population (PubMed:9271401). Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells (PubMed:12446708).
Represses myogenic differentiation by inhibiting MEFC acitivity (PubMed:22956541). Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli (PubMed:9271401, PubMed:22956541).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Foxk1 |
| Uniprot: | P42128 |
| Entrez: | 17425 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ14977; forkhead box K1; forkhead box protein K1; FoxK1; FOXK1L; IMAGE:5164497; MNF; Myocyte nuclear factor
Molecular Weight
Mass (kDA):
74.92 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 5 G2|5 81.53 cM |
| Sequence: | 5; |
Tissue Specificity
Expressed in tissues and cells in which the myoglobin gene is transcriptionally active including cardiac and skeletal myocytes, brain and kidney. In the adult brain, expressed in the piriform cortex and the indusium griseum. In the hippocampus, expression is localized to the dentate gyrus and CA3 area. In the cerebellum, expression is confined to the Purkinje cell layer.
Diseases
- Cell Transformation, Neoplastic
- Muscle Injury
- Muscular Dystrophy
- Malnutrition
- Olfaction Disorders
- Parkinson Disease
- Carcinogenesis
- Neoplasms
- Dystrophy
- Basal Cell Carcinoma
- Neurodegenerative Disorders
- Anosmia
- Epidermodysplasia Verruciformis
Pathways
- Regeneration
- Cell Cycle
- Reverse Transcription
- Cell Proliferation
- Cell Cycle Arrest
- Senescence
- Regulation Of Cell Cycle
- Cell Activation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Foxk1
bosterbio.com/bosterbio-gene-info-cards/Foxk1
References
PMID: 8007964 by Bassel-Duby R., et al. Myocyte nuclear factor, a novel winged-helix transcription factor under both developmental and neural regulation in striated myocytes.
PMID: 9271401 by Yang Q., et al. Transient expression of a winged-helix protein, MNF-beta, during myogenesis.