FEZ1 Antibodies

AND FEZ1 ELISA kits, FEZ1 Proteins

Many biological assays use antibodies to detect FEZ1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FEZ1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FEZ1 antibodies...

We validate the specificity of these antibodies to FEZ1 by testing them on tissues known to express FEZ1 positively and negatively. Browse below to find the FEZ1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FEZ1 Infographic by Boster Bio

All FEZ1 Products

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Product

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Specificity

Applications

Price

Anti-FEZ1 Antibody

Human, Mouse, Rat

ELISA, WB

$449
Cat # A04986
0.1 mg

FEZ1 (NM_005103) Human Over-expression Lysate

Human

$628
Cat # LS009638
100 µg

FEZ1 Overview

Facts about Fasciculation and elongation protein zeta-1.

FEZ1 3D structure. Source: alphafold

Fasciculation and elongation protein zeta-1 (FEZ1)

May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Willing to restore partial locomotion and axonal fasciculation to C.

elegans unc-76 mutants in germline transformation experiments. May take part in the transportation of mitochondria and other cargos along microtubules.

Gene Information

Human
Gene Name:	FEZ1
Uniprot:	Q99689
Entrez:	9638

Family

Belongs to:

zygin family

Alternative Names

fasciculation and elongation protein zeta 1 (zygin I); fasciculation and elongation protein zeta-1; Zygin I; zygin-1

Molecular Weight

Mass (kDA):
45.119 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (125442881..125496310, complement)

Tissue Specificity

Mainly expressed in brain.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell membrane. Colocalizes with both, alpha- and gamma-tubulin. Translocated from the plasma membrane to the cytoplasm by activation of the PKC zeta (By similarity).

Diseases

Muscular Fasciculation
Malignant Neoplasms
Neoplasms
Schizophrenia
Carcinoma
Mental Disorders
Bipolar Disorder
Nervousness
Malignant Neoplasm Of Urinary Bladder
Tumor Progression
Psychotic Disorders
Carcinogenesis

Bladder Neoplasm
Cell Transformation, Neoplastic
Pheochromocytoma
Adenocarcinoma
Malignant Paraganglionic Neoplasm
Prostatic Neoplasms
Carcinoma, Transitional Cell

Interacting Proteins

CEP126
HTT
NEK1
TXNDC9

Pathways

Transport
Localization
Cell Cycle
Mitosis
Cell Growth
Methylation
Rna Interference
M Phase
Nuclear Transport
Regulation Of Mitosis
Pathogenesis
Proteolysis
Chromosome Segregation

Anaphase
Prophase
Metaphase
Neuron Development
Regulation Of Cell Growth
Synaptic Vesicle Transport
Axonal Fasciculation

PTMs

Phosphorylation
Methylation

Dephosphorylation
Myristoylation

Research Areas

Apoptosis
Cancer
Tumor Suppressors

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FEZ1

References

PMID: 9096408 by Bloom L., et al. The Caenorhabditis elegans gene unc-76 and its human homologs define a new gene family involved in axonal outgrowth and fasciculation.

PMID: 15466860 by Okumura F., et al. Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis.