F-box only protein 3 Antibodies

AND FBXO3 ELISA kits, F-box only protein 3 Proteins

Many biological assays use antibodies to detect F-box only protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F-box only protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F-box only protein 3 antibodies...

We validate the specificity of these antibodies to F-box only protein 3 by testing them on tissues known to express FBXO3 positively and negatively. Browse below to find the FBXO3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBXO3 Infographic by Boster Bio

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FBXO3 (NM_012175) Human Recombinant Protein

$1062
Cat # PROTQ9UK99
20 µg

FBXO3 (NM_012175) Human Over-expression Lysate

Human

$628
Cat # LS026273
100 µg

FBXO3 Overview

Facts about F-box only protein 3.

FBXO3 3D structure. Source: alphafold

F-box only protein 3 (FBXO3)

Substrate recognition part of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome.

In the presence of PML, HIPK2 ubiquitination still happens, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to trigger p53/TP53- dependent transactivation.