FAM107A Antibodies

AND FAM107A ELISA kits, FAM107A Proteins

Many biological assays use antibodies to detect FAM107A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FAM107A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FAM107A antibodies...

We validate the specificity of these antibodies to FAM107A by testing them on tissues known to express FAM107A positively and negatively. Browse below to find the FAM107A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FAM107A Infographic by Boster Bio

All FAM107A Products

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Product

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Specificity

Applications

Price

Anti-FAM107A Antibody

Human, Mouse

$405
Cat # A08424
100ul

FAM107A (NM_001076778) Human Recombinant Protein

$813
Cat # PROTO95990
20 µg

FAM107A (NM_001076778) Human Over-expression Lysate

Human

$628
Cat # LS011170
100 µg

FAM107A Overview

Facts about Actin-associated protein FAM107A.

FAM107A 3D structure. Source: alphafold

Actin-associated protein FAM107A (FAM107A)

Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin into F-actin.

Also binds to, stabilizes and packages F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity).

Gene Information

Human
Gene Name:	FAM107A
Uniprot:	O95990
Entrez:	11170

Family

Belongs to:

FAM107 family

Alternative Names

downregulated in renal cell carcinoma; DRR1family with sequence similarity 107 member A transcript; family with sequence similarity 107, member A; FLJ30158; FLJ45473; Protein TU3A; TU3ADown-regulated in renal cell carcinoma 1

Molecular Weight

Mass (kDA):
17.455 kDA

Genomic Context


Human

Location:	3p14.3-p14.2
Sequence:	3; NC_000003.12 (58564117..58627610, complement)

Tissue Specificity

Widely expressed (PubMed:10564580). Expressed in neurons (PubMed:20543869). Expressed in malignant glial tumors (PubMed:20543869). Expression is reduced or absent in a number of cancer cell lines (PubMed:10564580).

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, stress fiber. Cell junction, focal adhesion. Cell projection, ruffle membrane. Cell junction, synapse. Colocalizes with F-actin and COMMD1 in the nucleus (PubMed:28604741). Colocalizes with MAP1A along actin stress fibers and membrane ruffles (PubMed:20543869).

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Renal Cell Carcinoma
Malignant Paraganglionic Neoplasm
Glioma
Kidney Neoplasm
Nervousness
Cell Transformation, Neoplastic
Tissue Adhesions
Brain Neoplasms
Malignant Neoplasm Of Breast

Mammary Neoplasms
Malignant Neoplasm Of Lung
Bipolar Disorder
Glioblastoma
Schizophrenia
Malignant Glioma
Growth Retardation

Interacting Proteins

FSD2
KRT40
LZTS2
PNMA1
RINT1

TRIM37
USHBP1

Pathways

Cell Growth
Transport
Clathrin-mediated Endocytosis
Cell Activation
Cell Migration
Electron Transport
Hypersensitivity
Regulation Of Gene Expression
Endocytosis
Localization
Mast Cell Activation
Embryo Development
Methylation

Cytokine Production
Translation
System Development
Mast Cell Degranulation
Cell Cycle
Cell Motility
Cell Death

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FAM107A

References

PMID: 10564580 by Wang L., et al. Loss of expression of the DRR1 gene at chromosomal segment 3p21.1 in renal cell carcinoma.

PMID: 10702698 by Yamato T., et al. Isolation and characterization of the novel gene, TU3A, in a commonly deleted region on 3p14.3->p14.2 in renal cell carcinoma.