F8A1 Antibodies

AND F8A1 ELISA kits, F8A1 Proteins

Many biological assays use antibodies to detect F8A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F8A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F8A1 antibodies...

We validate the specificity of these antibodies to F8A1 by testing them on tissues known to express F8A1 positively and negatively. Browse below to find the F8A1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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F8A1 Infographic by Boster Bio

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HAP40 (F8A1) (NM_012151) Human Over-expression Lysate

Human

$628
Cat # LS008263
100 µg

F8A1 Overview

Facts about 40-kDa huntingtin-associated protein.

F8A1 3D structure. Source: alphafold

40-kDa huntingtin-associated protein (F8A1)

Not known. Possible housekeeping role.

Gene Information

Human
Gene Name:	F8A1
Uniprot:	P23610
Entrez:	8263

Family

Belongs to:

No superfamily

Alternative Names

40-kDa huntingtin-associated protein

Molecular Weight

Mass (kDA):
39.103 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (154886360..154888061)

Tissue Specificity

Produced abundantly in a wide variety of cell types.

Subcellular Localizations

Cytoplasm. Nucleus. Early endosome. Nucleus, nuclear body. Diffuse presence in the cytoplasm and accumulation in the nucleus (PubMed:16476778). In absence of HTT, F8A1/F8A2/F8A3 is concentred in cytoplasm (By similarity). Colocalized with HTT in endosomes (PubMed:16476778). In neuron found in intranuclear structures, the intranuclear rodlets (INRs), also known as rodlets of Roncoroni, in association with ubiquitin (By similarity).

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F8A1

References

PMID: 2110545 by Levinson B., et al. A transcribed gene in an intron of the human factor VIII gene.

PMID: 16476778 by Pal A., et al. Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease.