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- Table of Contents
Facts about Exocyst complex component 3.
Human | |
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Gene Name: | EXOC3 |
Uniprot: | O60645 |
Entrez: | 11336 |
Belongs to: |
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SEC6 family |
exocyst complex component 3; Exocyst complex component Sec6; Sec 6 homolog; SEC6; SEC6L1; SEC6-like 1 (S. cerevisiae); SEC6-like 1; Sec6p
Mass (kDA):
85.567 kDA
Human | |
---|---|
Location: | 5p15.33 |
Sequence: | 5; NC_000005.10 (443176..467290) |
Expressed in epididymis (at protein level).
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. Midbody. Golgi apparatus. Cell projection, neuron projection. Perinuclear in undifferentiated cells. Redistributes to growing neurites and growth cones during neuronal differentiation (By similarity). During mitosis, early recruitment to the midbody requires RALA, but not RALB, and EXOC2. In late stages of cytokinesis, localization to the midbody is RALB-dependent (PubMed:18756269).
PMID: 20736409 by Li J., et al. Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins.
PMID: 12693554 by Jikuya H., et al. Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones.