EVI5 Antibodies

AND EVI5 ELISA kits, EVI5 Proteins

Many biological assays use antibodies to detect EVI5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EVI5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EVI5 antibodies...

We validate the specificity of these antibodies to EVI5 by testing them on tissues known to express EVI5 positively and negatively. Browse below to find the EVI5 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EVI5 Infographic by Boster Bio

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EVI5 (NM_005665) Human Over-expression Lysate

Human

$960
Cat # LS007813
100 µg

EVI5 Overview

Facts about Ecotropic viral integration site 5 protein homolog.

EVI5 3D structure. Source: alphafold

Ecotropic viral integration site 5 protein homolog (EVI5)

Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and boosting cyclin-A accumulation during interphase. May play a role in cytokinesis.

Gene Information

Human
Gene Name:	EVI5
Uniprot:	O60447
Entrez:	7813

Family

Belongs to:

No superfamily

Alternative Names

dJ846D11.1 (ecotropic viral integration site 5); ecotropic viral integration site 5 protein homolog; ecotropic viral integration site 5; EVI-5; NB4SNeuroblastoma stage 4S gene protein

Molecular Weight

Mass (kDA):
92.949 kDA

Genomic Context


Human

Location:	1p22.1
Sequence:	1; NC_000001.11 (92508696..92792413, complement)

Tissue Specificity

Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal.

Subcellular Localizations

Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.

Diseases

Sclerosis
Multiple Sclerosis
Neoplasms
Dysequilibrium Syndrome
Neuroblastoma
Chromosomal Translocation
Melanoma
Stage 4s Neuroblastoma
Neoplasm Metastasis
Mutation Abnormality
Metastatic Malignant Neoplasm To The Liver
Eye Neoplasms
Malignant Neoplasms

Exhaustion
Lymphoma
Anaplasia
T-cell Lymphoma
Mesothelioma
Cell Transformation, Neoplastic
Leukemogenesis

Interacting Proteins

DLG1
FBXO5
PLK1
RAB11A

Pathways

Cell Cycle
Mitosis
Transport
Interphase
Localization
Cellular Senescence
Cytokinesis
Senescence
Histolysis
Cell Migration
Anaphase
Cell Division
Translation

Chromatin Remodeling
Cell Dedifferentiation
Intracellular Transport
Endocytosis
Endosome Organization
Abscission
Regeneration

PTMs

Phosphorylation

Cleavage

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EVI5

References

PMID: 9618176 by Roberts T., et al. NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma.

PMID: 19077034 by Ishibashi K., et al. Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity.