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ERP44 Antibodies
AND ERP44 ELISA kits, ERP44 Proteins
Many biological assays use antibodies to detect ERP44, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ERP44 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ERP44 antibodies...
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ERP44 Overview
Facts about Endoplasmic reticulum resident protein 44.
Endoplasmic reticulum resident protein 44 (ERP44)
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1.
May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to keep ERO1A and ERO1B in the endoplasmic reticulum.
Gene Information
| Human | |
|---|---|
| Gene Name: | ERP44 |
| Uniprot: | Q9BS26 |
| Entrez: | 23071 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
endoplasmic reticulum protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; ERp44; KIAA0573endoplasmic reticulum resident protein 44; PDIA10; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4; TXNDC4
Molecular Weight
Mass (kDA):
46.971 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q31.1 |
| Sequence: | 9; NC_000009.12 (99979185..100099000, complement) |
Subcellular Localizations
Endoplasmic reticulum lumen.
Diseases
- Diabetes Mellitus
- Diabetes Mellitus, Non-insulin-dependent
- Obesity
- Endoplasmic Reticulum Stress
- Insulin Resistance
- Cardiovascular Diseases
- Malnutrition
- Coronary Heart Disease
- Melanoma
- Neurodegenerative Disorders
- Malignant Neoplasms
- Nervousness
- Retroviridae Infections
Interacting Proteins
- LMAN1
Pathways
- Secretion
- Localization
- Protein Folding
- Secretory Pathway
- Adiponectin Secretion
- Protein Secretion
- Cell Death
- Pathogenesis
- Transport
- Regulation Of Energy Homeostasis
- Saliva Secretion
- Insulin Secretion
- Fertilization
PTMs
- Oxidation
- Phosphorylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ERP44
bosterbio.com/bosterbio-gene-info-cards/ERP44
References
PMID: 11847130 by Anelli T., et al. ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family.
PMID: 14517240 by Anelli T., et al. Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44.