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EPCAM Antibodies
AND EPCAM ELISA kits, EPCAM Proteins
Many biological assays use antibodies to detect EPCAM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EPCAM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EPCAM antibodies...
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EPCAM Infographic by Boster Bio
All EPCAM Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK0755
96 wells/kit, with removable strips.
Cat # EK0755
96 wells/kit, with removable strips.
Anti-EpCAM Antibody Picoband®
5 Citations 16 Q&As
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # PB10059
100 μg/vial
Cat # PB10059
100 μg/vial
Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody
3 Citations 15 Q&As
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # M30950-1
100 μl
Cat # M30950-1
100 μl
Anti-EpCAM/Trop1 Rabbit Monoclonal Antibody
2 Citations 16 Q&As
Human
IHC, WB
$370
Cat # M30950-2
100 μl
Cat # M30950-2
100 μl
Human
ELISA
$499
Cat # FEK0755
96 wells/kit, with removable strips.
Cat # FEK0755
96 wells/kit, with removable strips.
Human
Flow Cytometry, IP, IHC-P, IHC-F, ICC, WB
$299
Cat # M00276
0.1 mg
Cat # M00276
0.1 mg
Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A00276-2
100 µg/vial
Cat # A00276-2
100 µg/vial
EPCAM Overview
Facts about Epithelial cell adhesion molecule.
Epithelial cell adhesion molecule (EPCAM)
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) in the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation.
Up-regulates the saying of FABP5, MYC and cyclins A and E. .
Gene Information
| Human | |
|---|---|
| Gene Name: | EPCAM |
| Uniprot: | P16422 |
| Entrez: | 4072 |
Family
| Belongs to: |
|---|
| EPCAM family |
Alternative Names
17-1A; 323/A3; ACSTD1; antigen identified by monoclonal AUA1; CD326 antigen; CD326; Cell surface glycoprotein Trop-1; chromosome 4, surface marker (35kD glycoprotein); DIAR5; EGP; EGP-2; EGP314; EGP40; EpCAM; epithelial cell adhesion molecule; Epithelial cell surface antigen; Epithelial glycoprotein 314; Epithelial glycoprotein; ESA; GA733-2; GA733-2EGP34; gp40; hEGP314; HNPCC8; KS 1/4 antigen; KS1/4; KSAHEA125; M1S2; M4S1; M4S1Ly74; Major gastrointestinal tumor-associated protein GA733-2; MIC18MH99; MOC31; TACST-1; TACSTD1; TROP1; TROP1CD326; Tumor-associated calcium signal transducer 1CO-17A
Molecular Weight
Mass (kDA):
34.932 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2p21 |
| Sequence: | 2; NC_000002.12 (47369311..47387020) |
Tissue Specificity
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
Subcellular Localizations
Lateral cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Colocalizes with CLDN7 at the lateral cell membrane and tight junction.
Diseases
- Malignant Neoplasms
- Neoplasms
- Tissue Adhesions
- Carcinoma
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Colorectal Cancer
- Adenocarcinoma
- Malignant Paraganglionic Neoplasm
- Liver Carcinoma
- Liver Neoplasms
- Colorectal Neoplasms
Pathways
- Cell Adhesion
- Cell Proliferation
- Localization
- Cell-cell Adhesion
- Methylation
- Immune Response
- Cell Migration
- Secretion
- Pathogenesis
- Cell Growth
- Mismatch Repair
- Regeneration
- Cell Cycle
PTMs
- Methylation
- Cleavage
- Phosphorylation
- Glycosylation
Research Areas
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPCAM
bosterbio.com/bosterbio-gene-info-cards/EPCAM
References
PMID: 2463074 by Strnad J., et al. Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA.
PMID: 2469722 by Perez M.S., et al. Isolation and characterization of a cDNA encoding the KS1/4 epithelial carcinoma marker.
6 Publications of Boster EPCAM Antibodies & ELISA Kits
- PubMed ID: 10.1039/C5AN00799B, Deformability and size-based cancer cell separation using an integrated microflu...
- PubMed ID: 10.1002/cbin.11598, Epithelial cell adhesion molecule promotes breast cancer resistance protein‐me...
- PubMed ID: , Performance of a multilayered small-diameter vascular scaffold dual-loaded with ...
- PubMed ID: 33069797, Shi R,Liu L,Wang F,He Y,Niu Y,Wang C,Zhang X,Zhang X,Zhang H,Chen M,Wang Y.Downr...
- PubMed ID: 27221035, A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migra...
- PubMed ID: 29179771, Zhang Q, Bu S, Sun J, Xu M, Yao X, He K, Lai D. Stem Cell Res Ther. 2017 Nov 28;...
*More publications can be found for each product on its corresponding product page