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- Table of Contents
Facts about Eukaryotic translation initiation factor 6.
Is also involved in ribosome biogenesis. Associates with pre-60S subunits from the nucleus and is involved in its nuclear export.
Human | |
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Gene Name: | EIF6 |
Uniprot: | P56537 |
Entrez: | 3692 |
Belongs to: |
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eIF-6 family |
B(2)GCN homolog; b(2)gcn; B4 integrin interactor; CAB; EIF3Ap27(BBP); eIF-6; eukaryotic translation initiation factor 3A; eukaryotic translation initiation factor 6; ITGB4BPintegrin beta 4 binding protein; p27 beta-4 integrin-binding protein; p27BBP
Mass (kDA):
26.599 kDA
Human | |
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Location: | 20q11.22 |
Sequence: | 20; NC_000020.11 (35278906..35284772, complement) |
Expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in kidney and muscle (at protein level).
Cytoplasm. Nucleus, nucleolus. Shuttles between cytoplasm and nucleus/nucleolus.
PMID: 9405604 by Si K., et al. Molecular cloning and functional expression of a human cDNA encoding translation initiation factor 6.
PMID: 9374518 by Biffo S., et al. Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells.