EHD1 Antibodies

EH domain-containing protein 1 (EHD1)

In vitro causes vesiculation of endocytic membranes (PubMed:24019528). Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:20801876).

Recruited into endosomal membranes upon nerve growth factor stimulation, indirectly modulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity).

Gene Information

Human
Gene Name:	EHD1
Uniprot:	Q9H4M9
Entrez:	10938

Family

Belongs to:
TRAFAC class dynamin-like GTPase superfamily

Alternative Names

EH-domain containing 1

Molecular Weight

Mass (kDA):
60.627 kDA

Genomic Context

Human
Location:	11q13.1
Sequence:	11; NC_000011.10 (64851642..64879713, complement)

Tissue Specificity

Highly expressed in testis.

Subcellular Localizations

Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Preferentially associates with tubular recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:19864458, PubMed:23596323). Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250). Colocalizes

Diseases

• Malignant Neoplasms
• Tissue Adhesions
• Neoplasms
• Obesity
• Dwarfism
• Fibrolamellar Carcinoma
• Stomach Neoplasms
• Glioma
• Spermatogenesis Abnormal
• Infertility
• Sarcoma

• Lymphoma
• Dysequilibrium Syndrome
• Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome
• Trematode Infections
• Muscle Injury
• Congenital Abnormality

Interacting Proteins

• ANKFY1
• EHD3
• Ehd3
• MICALL1
• RBSN

Pathways

• Endocytic Recycling
• Transport
• Endocytosis
• Localization
• Receptor Recycling
• Clathrin-mediated Endocytosis
• Endosomal Transport
• Rna Interference
• Cell Adhesion
• Exocytosis
• Transcytosis
• Cell Proliferation
• Cell Migration

• Protein Targeting
• Ossification
• Nuclear Export
• Spermatogenesis
• Cytokinesis
• Glucose Homeostasis
• Axon Guidance

PTMs

• Phosphorylation
• Sumoylation

• Methylation
• Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EHD1

Boster Bio Antibodies - Best Uses Of The EHD1 Marker

If you've been looking for the best boster bio antibodies, you've come to the right place. This article will cover the best uses for Boster Bio Anti-KHDRBS2 Antibody, Boster Bio Anti-Bax (S4) Antibody, and Boster Bio EHD1 Antibody Picoband(tm).

Boster Bio Anti-KHDRBS2 Antibody

The Boster Bio Anti-KHDRBS2-antibody is tested for human and mouse. The antibody can be used for IHC and WB applications. It is supplied in a Liquid form, but can also be used for IP and ELISA. It can be used in a variety of applications, including immunohistochemistry and western blotting.

Boster Bio Anti-Bax (S4) Antibody

Boster Bio offers high-affinity primary antibodies for this protein. These antibodies have been validated in Immunohistochemistry, ELISA, and Western Blotting. They react with Human, Mouse, and Rat. A blocking peptide is also available to control EHD1-specific antibodies. All Boster antibodies are tested for safety and efficiency in laboratory tests.

Boster Bio Anti-EHD1 Antibody Picoband(tm)

The Boster Bio Anti-EHD1 antibody is a primary antibody specific for human EHD1. This protein, also known as DNM1L, is one of the most important markers in the process of mitochondrial fission. The DNM1L gene encodes this protein, which is involved in developmentally regulated apoptosis and programmed necrosis. The protein has been implicated in the development of Alzheimer's disease, a condition characterized by defective mitochondrial and peroxisomal fission. Its antibody binds to phospholipids and forms homodimers through a coiled coil. The antibody is also important in coupling vesicle docking with SNAREs, which is necessary for endosomal cargo delivery. Boster validates all