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- Table of Contents
1 Q&As
Facts about EH domain-containing protein 1.
Recruited into endosomal membranes upon nerve growth factor stimulation, indirectly modulates neurite outgrowth (By similarity). Plays a role in myoblast fusion (By similarity).
Human | |
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Gene Name: | EHD1 |
Uniprot: | Q9H4M9 |
Entrez: | 10938 |
Belongs to: |
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TRAFAC class dynamin-like GTPase superfamily |
EH-domain containing 1
Mass (kDA):
60.627 kDA
Human | |
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Location: | 11q13.1 |
Sequence: | 11; NC_000011.10 (64851642..64879713, complement) |
Highly expressed in testis.
Recycling endosome membrane; Peripheral membrane protein; Cytoplasmic side. Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Preferentially associates with tubular recycling endosomes (PubMed:15020713, PubMed:17233914, PubMed:19864458, PubMed:23596323). Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity). Localizes to the ciliary pocket from where the cilium protrudes (PubMed:25686250). Colocalizes
PMID: 9253601 by Guru S.C., et al. A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus.
PMID: 10395801 by Mintz L., et al. EHD1 -- an EH-domain-containing protein with a specific expression pattern.