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- Table of Contents
Facts about Eukaryotic translation elongation factor 1 epsilon-1.
Human | |
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Gene Name: | EEF1E1 |
Uniprot: | O43324 |
Entrez: | 9521 |
Belongs to: |
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No superfamily |
AIMP3Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3; ARS-interacting multifunctional protein 3; Elongation factor p18; eukaryotic translation elongation factor 1 epsilon 1; eukaryotic translation elongation factor 1 epsilon-1; Multisynthase complex auxiliary component p18; p18 component of aminoacyl-tRNA synthetase complex; P18
Mass (kDA):
19.811 kDA
Human | |
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Location: | 6p24.3 |
Sequence: | 6; NC_000006.12 (8073360..8102548, complement) |
Down-regulated in various cancer tissues.
Cytoplasm. Cytoplasm, cytosol. Nucleus. Cytoplasmic under growth arrest conditions. Translocated into the nucleus when growth resumes (S phase) and following DNA damage.
PMID: 9653160 by Mao M., et al. Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full- length cDNA cloning.
PMID: 15680327 by Park B.-J., et al. The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR.