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- Table of Contents
Facts about Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial.
Involved in the BMP signaling pathway. Required for normal embryonic development.
Mouse | |
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Gene Name: | Ecsit |
Uniprot: | Q9QZH6 |
Entrez: | 26940 |
Belongs to: |
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ECSIT family |
ECSIT homolog (Drosophila); evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarilyconserved; Protein SITPEC; signaling intermediate in Toll pathway evolutionarily conserved ortholog; SITPECsignaling intermediate in Toll pathway, evolutionarily conserved
Mass (kDA):
49.799 kDA
Mouse | |
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Location: | 9|9 A3 |
Sequence: | 9; |
Detected in heart, brain, lung, liver, skeletal muscle, kidney and testis. Detected in embryonic mesoderm and epiblast, and in extraembryonic ectoderm.
PMID: 10465784 by Kopp E., et al. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway.
PMID: 14633973 by Xiao C., et al. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis.