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- Table of Contents
Facts about Dynein light chain Tctex-type 1.
Binds to transport cargos and is involved in apical freight transport such as rhodopsin-bearing vesicles in polarized epithelia. May also be a accessory component of axonemal dynein.
Human | |
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Gene Name: | DYNLT1 |
Uniprot: | P63172 |
Entrez: | 6993 |
Belongs to: |
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dynein light chain Tctex-type family |
Dynein light chain Tctex-type 1
Mass (kDA):
12.452 kDA
Human | |
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Location: | 6q25.3 |
Sequence: | 6; NC_000006.12 (158636474..158644743, complement) |
Expressed in heart, placenta, skeletal muscle kidney, pancreas, spleen, prostate, testis, ovary, ileum and colon. Expressed in lung endothelial and smooth muscle cells (at protein level).
Golgi apparatus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Localizes to mitotic spindles.
PMID: 8646886 by Watanabe T.K., et al. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q.
PMID: 11751937 by Mueller S., et al. Interaction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesis.