Docking protein 3 Antibodies

AND Dok3 ELISA kits, Docking protein 3 Proteins

Many biological assays use antibodies to detect Docking protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Docking protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Docking protein 3 antibodies...

We validate the specificity of these antibodies to Docking protein 3 by testing them on tissues known to express Dok3 positively and negatively. Browse below to find the Dok3 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Dok3 Infographic by Boster Bio

All Dok3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Docking protein 3 DOK3 Antibody

5 Q&As

Human, Mouse

$360
Cat # A09019-1
100 µl

Anti-Dok-3 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A09019
100ul

DOK3 (NM_024872) Human Recombinant Protein

$1249
Cat # PROTQ7L591
20 µg

Anti-DOK3 Mouse Monoclonal Antibody [Clone ID: OTI2B11]

Human, Mouse

$523
Cat # M09019-1
100 µl

Anti-DOK3 Mouse Monoclonal Antibody [Clone ID: OTI3G9]

Human, Mouse

$523
Cat # M09019
100 µl

DOK3 (NM_024872) Human Over-expression Lysate

Human

$960
Cat # LS079930
100 µg

Dok3 Overview

Facts about Docking protein 3.

Docking protein 3 (Dok3)

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes.

DOK3 is a negative regulator of JNK signaling in B-cells through interaction with INPP5D/SHIP1. May modulate ABL1 function.

Gene Information

Mouse
Gene Name:	Dok3
Uniprot:	Q9QZK7
Entrez:	27261

Family

Belongs to:

DOK family

Alternative Names

docking protein 3; DOK3; DOKL; Dok-like protein; Downstream of tyrosine kinase 3; FLJ22570; FLJ39939

Molecular Weight

Mass (kDA):
48.027 kDA

Genomic Context


Mouse

Location:	13\|13 B1
Sequence:	13;

Tissue Specificity

Predominantly expressed in bone marrow, spleen and lung. Low levels in heart, brain, liver, muscle, thymus, kidney and testis. Highly expressed in B-cells and macrophages.

Diseases

Malignant Neoplasms
Neoplasms
Cell Invasion
Histiocytic Sarcoma
Adenocarcinoma
Rectal Carcinoma
Hematologic Neoplasms
Lung Neoplasms
Colonic Neoplasms
Myeloid Leukemia, Chronic
Sarcoma
Malignant Neoplasm Of Lung

Myeloid Leukemia
Leukemia
Kidney Diseases
Colorectal Cancer
Rectal Neoplasms
Adenocarcinoma Of Lung (disorder)

Pathways

Localization
Cell Activation
Cell Proliferation
Cytokine Production
Cell Cycle
Cell Death
Jnk Cascade

T Cell Activation
B Cell Activation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dok3

References

PMID: 10567556 by Cong F., et al. Characterization of a novel member of the DOK family that binds and modulates Abl signaling.

PMID: 10733577 by Lemay S., et al. Dok-3, a novel adapter molecule involved in the negative regulation of immunoreceptor signaling.