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DNAJA1 Antibodies
AND DNAJA1 ELISA kits, DNAJA1 Proteins
Many biological assays use antibodies to detect DNAJA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNAJA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNAJA1 antibodies...
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DNAJA1 Infographic by Boster Bio
All DNAJA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IF, ICC, WB
$370
Cat # PA1597
100 μg/vial
Cat # PA1597
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M04151
100 μl/vial
Cat # M04151
100 μl/vial
DNAJA1 Overview
Facts about DnaJ homolog subfamily A member 1.
DnaJ homolog subfamily A member 1 (DNAJA1)
Co-chaperone for HSPA8/Hsc70 (PubMed:10816573).
Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877).Plays a role in protein transport into mitochondria via its role as co- chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol into mitochondria in response to cellular stress, thereby protecting cells from apoptosis (PubMed:14752510).
Gene Information
| Human | |
|---|---|
| Gene Name: | DNAJA1 |
| Uniprot: | P31689 |
| Entrez: | 3301 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
dj-2; DjA1; DnaJ (Hsp40) homolog, subfamily A, member 1; dnaJ homolog subfamily A member 1; DnaJ protein homolog 2; DNAJ2; HDJ2; hDJ-2; Heat shock 40 kDa protein 4; Heat shock protein J2; heat shock protein, DNAJ-like 2; HSDJ; HSJ2; HSJ-2; HSPF4hdj-2; Human DnaJ protein 2; NEDD7; neural precursor cell expressed, developmentally down-regulated 7
Molecular Weight
Mass (kDA):
44.868 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p21.1 |
| Sequence: | 9; NC_000009.12 (33025203..33039907) |
Tissue Specificity
Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.
Subcellular Localizations
Membrane; Lipid-anchor. Cytoplasm. Microsome. Nucleus. Cytoplasm, perinuclear region. Mitochondrion. Primarily associated with microsomes. A minor proportion is associated with mitochondria (By similarity). Primarily cytoplasmic. A minor proportion is associated with nuclei.
Diseases
- Malignant Neoplasms
- Neoplasms
- Neurodegenerative Disorders
- Sore To Touch
- Cystic Fibrosis
- Fibrosis
- Malignant Neoplasm Of Breast
- Diarrhea
- Anemia
- Pancreatic Neoplasm
- Leukemia
- Ataxia
- Tumor Angiogenesis
Interacting Proteins
- AICDA
Pathways
- Protein Folding
- Prenylation
- Cell Death
- Cell Cycle
- Localization
- Cell Cycle Arrest
- Spermatogenesis
- Translation
- Protein Import
- Protein Farnesylation
- Protein Prenylation
- Cytokine Production
- Angiogenesis
PTMs
- Farnesylation
- Prenylation
- Phosphorylation
- Geranylgeranylation
Research Areas
- DNA Repair
- Golgi Apparatus Markers
- Membrane Trafficking and Chaperones
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNAJA1
bosterbio.com/bosterbio-gene-info-cards/DNAJA1
References
PMID: 8334161 by Oh S., et al. Human cDNA encoding DnaJ protein homologue.
PMID: 8334160 by Chellaiah A., et al. Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein.