DLGAP5 Antibodies

AND DLGAP5 ELISA kits, DLGAP5 Proteins

Many biological assays use antibodies to detect DLGAP5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DLGAP5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DLGAP5 antibodies...

We validate the specificity of these antibodies to DLGAP5 by testing them on tissues known to express DLGAP5 positively and negatively. Browse below to find the DLGAP5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DLGAP5 Infographic by Boster Bio

All DLGAP5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-HURP DLGAP5 Antibody

Human

$399
Cat # A05112
100μl

Anti-DLGAP5/Hurp Antibody

4 Q&As

Human, Mouse, Rat

ELISA, WB

$335
Cat # A30642
100ul

Anti-DLGAP5 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A05112-1
100ul

HURP (DLGAP5) (NM_014750) Human Over-expression Lysate

Human

$628
Cat # LS009787
100 µg

DLGAP5 Overview

Facts about Disks large-associated protein 5.

DLGAP5 3D structure. Source: alphafold

Disks large-associated protein 5 (DLGAP5)

Potential cell cycle regulator which may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway.

Key regulator of adherens junction integrity and distinction which may be involved in CDH1-mediated adhesion and signaling in epithelial cells. .

Gene Information

Human
Gene Name:	DLGAP5
Uniprot:	Q15398
Entrez:	9787

Family

Belongs to:

SAPAP family

Alternative Names

DAP-5; Discs large homolog 7; discs, large (Drosophila) homolog-associated protein 5; disks large-associated protein 5; DLG7; Hepatoma up-regulated protein; HURPDLG1; KIAA0008discs, large homolog 7 (Drosophila); large homolog 7

Molecular Weight

Mass (kDA):
95.115 kDA

Genomic Context


Human

Location:	14q22.3
Sequence:	14; NC_000014.9 (55148130..55191585, complement)

Tissue Specificity

Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Localizes to the spindle in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.

Diseases

Carcinoma
Malignant Neoplasms
Liver Carcinoma
Neoplasms
Liver Neoplasms
Carcinogenesis
Carcinoma, Transitional Cell
Malignant Neoplasm Of Adrenal Cortex
Tumors Of Adrenal Cortex
Liver Regeneration Disorder
Bladder Neoplasm
Cell Transformation, Neoplastic

Hyperplasia
Malignant Neoplasm Of Breast
Colonic Neoplasms
Malignant Tumor Of Colon
Malignant Neoplasm Of Liver
Aneuploidy
Benign Prostatic Hypertrophy

Interacting Proteins

GOLGA2
MTUS2

Pathways

Spindle Assembly
Mitosis
Cell Cycle
Anaphase
Localization
Metaphase
Spindle Checkpoint
Cell Proliferation
Cell Death
Transport
Proteolysis
Chromosome Segregation
Nuclear Export

Cytokinesis
Cell Division
Microtubule Nucleation
Reverse Transcription
Translation
Liver Regeneration
Interphase

PTMs

Phosphorylation

Ubiquitination

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DLGAP5

References

PMID: 12527899 by Tsou A.-P., et al. Identification of a novel cell cycle regulated gene, HURP, overexpressed in human hepatocellular carcinoma.

PMID: 14699157 by Laprise P., et al. Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells.