Protein DGCR6 Antibodies

AND DGCR6 ELISA kits, Protein DGCR6 Proteins

Many biological assays use antibodies to detect Protein DGCR6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein DGCR6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein DGCR6 antibodies...

We validate the specificity of these antibodies to Protein DGCR6 by testing them on tissues known to express DGCR6 positively and negatively. Browse below to find the DGCR6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DGCR6 Infographic by Boster Bio

All DGCR6 Products

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Specificity

Applications

Price

DGCR6 (NM_005675) Human Recombinant Protein

$813
Cat # PROTQ14129
20 µg

DGCR6 (NM_005675) Human Over-expression Lysate

Human

$628
Cat # LS008214
100 µg

DGCR6 Overview

Facts about Protein DGCR6.

DGCR6 3D structure. Source: alphafold

Protein DGCR6 (DGCR6)

May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. .

Gene Information

Human
Gene Name:	DGCR6
Uniprot:	Q14129
Entrez:	8214

Family

Belongs to:

gonadal family

Alternative Names

DiGeorge syndrome critical region 6; DiGeorge syndrome critical region gene 6; DiGeorge syndrome critical region protein 6; protein DGCR6

Molecular Weight

Mass (kDA):
24.989 kDA

Genomic Context


Human

Location:	22q11.21\|22q11
Sequence:	22; NC_000022.11 (18906320..18912088)

Tissue Specificity

Found in all tissues examined with highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain.

Subcellular Localizations

Nucleus. Predominantly nuclear.

Diseases

Digeorge Syndrome
Schizophrenia
Schizoaffective Disorder
Neoplasms
Crest Syndrome
Psychotic Disorders
Neoplasm Metastasis
Conotruncal Heart Malformations (disorder)
Malignant Neoplasm Of Breast
Human Mammary Carcinoma
Carcinoma
Tumor Angiogenesis

Animal Mammary Neoplasms
Malignant Neoplasms
Nervousness
Chromosome Breakage
Dysequilibrium Syndrome
Mammary Neoplasms, Experimental
Cell Invasion

Pathways

Cell Migration
Neural Crest Cell Migration
Synaptic Transmission
Angiogenesis
Meiosis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DGCR6

References

PMID: 11157784 by Edelmann L., et al. Two functional copies of the DGCR6 gene are present on human chromosome 22q11 due to a duplication of an ancestral locus.

PMID: 15821931 by Pfuhl T., et al. Biochemical characterisation of the proteins encoded by the DiGeorge critical region 6 (DGCR6) genes.