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- Table of Contents
Facts about Diacylglycerol O-acyltransferase 1.
May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol.
Human | |
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Gene Name: | DGAT1 |
Uniprot: | O75907 |
Entrez: | 8694 |
Belongs to: |
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membrane-bound acyltransferase family |
ACAT-related gene product 1; AGRP1; ARAT; ARGP1; ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1; DGAT; DGAT1; DGATACAT related gene product 1; diacylglycerol O-acyltransferase 1; diacylglycerol O-acyltransferase homolog 1 (mouse); diacylglycerol O-acyltransferase homolog 1; DIAR7; Diglyceride acyltransferase; EC 2.3.1; EC 2.3.1.20
Mass (kDA):
55.278 kDA
Human | |
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Location: | 8q24.3 |
Sequence: | 8; NC_000008.11 (144314584..144326852, complement) |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
PMID: 9756920 by Oelkers P., et al. Characterization of two human genes encoding acyl coenzyme A:cholesterol acyltransferase-related enzymes.
PMID: 16214399 by Orland M.D., et al. Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.