DDX42 Antibodies

AND DDX42 ELISA kits, DDX42 Proteins

Many biological assays use antibodies to detect DDX42, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DDX42 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DDX42 antibodies...

We validate the specificity of these antibodies to DDX42 by testing them on tissues known to express DDX42 positively and negatively. Browse below to find the DDX42 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DDX42 Infographic by Boster Bio

All DDX42 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DDX42 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A09904
100ul

DDX42 (NM_203499) Human Over-expression Lysate

Human

$960
Cat # LS011325
100 µg

DDX42 Overview

Facts about ATP-dependent RNA helicase DDX42.

DDX42 3D structure. Source: alphafold

ATP-dependent RNA helicase DDX42 (DDX42)

Binds to partly double- stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is encouraged in the presence of single-strand binding proteins.

Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 activates RNA strand separation, whereas the ADP-bound form of the protein activates annealing of complementary RNA strands.

Gene Information

Human
Gene Name:	DDX42
Uniprot:	Q86XP3
Entrez:	11325

Family

Belongs to:

DEAD box helicase family

Alternative Names

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42; DEAD box protein 42; EC 3.6.1; EC 3.6.4.13; RHELPSF3b DEAD box protein; RNA helicase-like protein; RNA helicase-related protein; RNAHPFLJ43179; SF3b125 DEAD-box protein; SF3b125ATP-dependent RNA helicase DDX42; Splicing factor 3B-associated 125 kDa protein

Molecular Weight

Mass (kDA):
102.975 kDA

Genomic Context


Human

Location:	17q23.3
Sequence:	17; NC_000017.11 (63773856..63819317)

Tissue Specificity

Expressed in several cell lines (at protein level). Expressed in liver, lung, tonsil, thymus, muscle and pancreatic islets.

Subcellular Localizations

Cytoplasm. Nucleus speckle. Nucleus, Cajal body. Isoform 2 is present in Cajal bodies (CBs) and nuclear speckles.

Diseases

Japanese Encephalitis
Anemia
Deficiency Anaemia
Diabetes Mellitus
Dengue Fever
Leukemia, Myelocytic, Acute
Iron Deficiency Anemia
Encephalitis
Diabetes Mellitus, Insulin-dependent
West Nile Viral Infection

Inflammation
Medulloblastoma
Anemia, Megaloblastic
Iron Deficiency
Dysmyelopoietic Syndromes

Pathways

Cell Growth
Cell Cycle
S Phase
Rna Processing
Ribosome Assembly
Pathogenesis
Freezing Tolerance

Spermatogenesis

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DDX42

References

PMID: 10727850 by Suk K., et al. Identification of a novel human member of the DEAD box protein family.

PMID: 12234937 by Will C.L., et al. Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein.