This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about L-xylulose reductase.
May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. .
Human | |
---|---|
Gene Name: | DCXR |
Uniprot: | Q7Z4W1 |
Entrez: | 51181 |
Belongs to: |
---|
short-chain dehydrogenases/reductases (SDR) family |
Carbonyl reductase II; DCR; dicarbonyl/L-xylulose reductaseP34H; EC 1.1.1; EC 1.1.1.10; HCR2; HCRII; human carbonyl reductase 2; KIDCR; Kidney dicarbonyl reductase; L-xylulose reductase; SDR20C1; short chain dehydrogenase/reductase family 20C, member 1; Sperm surface protein P34H; XR
Mass (kDA):
25.913 kDA
Human | |
---|---|
Location: | 17q25.3 |
Sequence: | 17; NC_000017.11 (82035858..82037697, complement) |
Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.
Membrane; Peripheral membrane protein. Probably recruited to membranes via an interaction with phosphatidylinositol.
PMID: 10385429 by Legare C., et al. P34H sperm protein is preferentially expressed by the human corpus epididymidis.
PMID: 11882650 by Nakagawa J., et al. Molecular characterization of mammalian dicarbonyl/L-xylulose reductase and its localization in kidney.