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Contactin-1 Antibodies
AND CNTN1 ELISA kits, Contactin-1 Proteins
Many biological assays use antibodies to detect Contactin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Contactin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Contactin-1 antibodies...
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CNTN1 Infographic by Boster Bio
All CNTN1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1771
96 wells/kit, with removable strips.
Cat # EK1771
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK1772
96 wells/kit, with removable strips.
Cat # EK1772
96 wells/kit, with removable strips.
Rat
ELISA
$499
Cat # EK1773
96 wells/kit, with removable strips.
Cat # EK1773
96 wells/kit, with removable strips.
Anti-Contactin 1/CNTN1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A04538-2
100 μg/vial
Cat # A04538-2
100 μg/vial
CNTN1 Overview
Facts about Contactin-1.
Contactin-1 (CNTN1)
Contactins mediate cell surface interactions during nervous system development. Involved in the creation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1.
Participates in oligodendrocytes creation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation into the nucleus.
Gene Information
| Human | |
|---|---|
| Gene Name: | CNTN1 |
| Uniprot: | Q12860 |
| Entrez: | 1272 |
Family
| Belongs to: |
|---|
| immunoglobulin superfamily |
Alternative Names
CNTN1; contactin 1; Contactin1; Contactin-1; F11; F3; F3cam; Glycoprotein gp135; GP135; Neural cell surface protein F3
Molecular Weight
Mass (kDA):
113.32 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q12 |
| Sequence: | 12; NC_000012.12 (40692429..41072415) |
Tissue Specificity
Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle.
Subcellular Localizations
[Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Isoform 2]: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Nervousness
- Neoplasms
- Cell Invasion
- Neoplasm Metastasis
- Metastatic Malignant Neoplasm To The Lymph Node
- Neoplasm Invasiveness
- Carcinoma
- Malignant Squamous Cell Neoplasm
- Lung Neoplasms
- Lymphatic Metastasis
- Myopathy
Interacting Proteins
- CNTNAP2
- PTPRZ1
Pathways
- Cell Adhesion
- Cell Proliferation
- Pathogenesis
- Lymphangiogenesis
- System Development
- Cell Cycle
- Localization
- Regeneration
- Nervous System Development
- Angiogenesis
- Rna Interference
- Secretion
- Cell Migration
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNTN1
bosterbio.com/bosterbio-gene-info-cards/CNTN1
References
PMID: 8164510 by Reid R.A., et al. Identification and characterization of the human cell adhesion molecule contactin.
PMID: 7959734 by Berglund E.O., et al. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12.
2 Publications of Boster Contactin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1097/BRS.0b013e31825d4ebc, Increased Expression of Netrin-1 and Its Deleted in Colorectal Cancer Receptor i...
- PubMed ID: 10.1007/s11010-011-0882-6, Id1-induced inhibition of p53 facilitates endothelial cell migration and tube fo...
*More publications can be found for each product on its corresponding product page