CHST15 Antibodies

AND CHST15 ELISA kits, CHST15 Proteins

Many biological assays use antibodies to detect CHST15, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHST15 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHST15 antibodies...

We validate the specificity of these antibodies to CHST15 by testing them on tissues known to express CHST15 positively and negatively. Browse below to find the CHST15 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: ZMYND10

CHST15 Infographic by Boster Bio

All CHST15 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CHSTF CHST15 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A07312
100ul

CHST15 (NM_015892) Human Over-expression Lysate

Human

$628
Cat # LS051363
100 µg

CHST15 Overview

Facts about Carbohydrate sulfotransferase 15.

CHST15 3D structure. Source: alphafold

Carbohydrate sulfotransferase 15 (CHST15)

Sulfotransferase that transfers sulfate from 3'- phosphoadenosine 5'-phosphosulfate (PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. Additionally, it transfers sulfate to a unique non- reducing terminal series, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield an extremely sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate.

May also act as a B- cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signs key to B-cell regulation or development of B-cell-specific RAG expression; however such results are unclear in vivo. .

Gene Information

Human
Gene Name:	CHST15
Uniprot:	Q7LFX5
Entrez:	51363

Family

Belongs to:

sulfotransferase 1 family

Alternative Names

B cell RAG associated protein (GALNAC4S-6ST); B-cell RAG-associated gene protein; BRAG; BRAGKIAA0598RP11-47G11.1; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; Carbohydrate Sulfotransferase 15; CHST15; DKFZp781H1369; EC 2.8.2.33; GALNAC4S6ST; GalNAc4S-6ST; hBRAG; MGC34346; N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase

Molecular Weight

Mass (kDA):
64.926 kDA

Genomic Context


Human

Location:	10q26.13
Sequence:	10; NC_000010.11 (124006059..124093684, complement)

Tissue Specificity

Expressed in B-cell-enriched tissues but not in fetal or adult thymus. Expressed in fetal and adult spleen, lymph node, tonsil, bone marrow and peripheral leukocytes. Not expressed in T-cells. In pro-B, pre-B, and mature B-cell lines, it colocalizes with RAG1.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein. A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.

Diseases

Circling Gait
Complete Hearing Loss
Vestibular Diseases

Interacting Proteins

CANX

Pathways

Sulfation
Cochlea Development

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHST15

References

PMID: 9754571 by Verkoczy L.K., et al. hBRAG, a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved in the regulation of recombination activating gene 1 (RAG1).

PMID: 11032940 by Yuki M., et al. Structure, expression and mutational analysis of the hBRAG gene on 10q in the frequently deleted region in human endometrial cancer.