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Chitotriosidase-1 Antibodies
AND CHIT1 ELISA kits, Chitotriosidase-1 Proteins
Many biological assays use antibodies to detect Chitotriosidase-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chitotriosidase-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chitotriosidase-1 antibodies...
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CHIT1 Infographic by Boster Bio
All CHIT1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK2032
96 wells/kit, with removable strips.
Cat # EK2032
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK2033
96 wells/kit, with removable strips.
Cat # EK2033
96 wells/kit, with removable strips.
CHIT1 Overview
Facts about Chitotriosidase-1.
Chitotriosidase-1 (CHIT1)
Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens.
Isoform 3 has no enzymatic activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHIT1 |
| Uniprot: | Q13231 |
| Entrez: | 1118 |
Family
| Belongs to: |
|---|
| glycosyl hydrolase 18 family |
Alternative Names
CHI3; CHIT1; CHITCHI3; chitinase 1 (chitotriosidase); chitinase-1; Chitotriosidase; chitotriosidase-1; EC 3.2.1.14; FLJ00314; MGC125322; plasma methylumbelliferyl tetra-N-acetylchitotetraoside hydrolase
Molecular Weight
Mass (kDA):
51.681 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.1 |
| Sequence: | 1; NC_000001.11 (203216079..203229673, complement) |
Tissue Specificity
Detected in spleen. Secreted by cultured macrophages.
Subcellular Localizations
Secreted. Lysosome. A small proportion is lysosomal.
Diseases
- Asthma
- Gaucher Disease
- Malaria
- Malaria, Falciparum
- Mycoses
- Filariasis
- Infective Disorder
- Sclerosis
- Lung Diseases
- Neoplasms
- Gaucher Disease, Type 1
- Inflammation
- Filarial Elephantiases
Pathways
- Pathogenesis
- Immune Response
- Macrophage Activation
- Macrophage Differentiation
- Fermentation
- Sensitization
- Tissue Remodeling
- Cell Differentiation
PTMs
- Disulfide bond
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHIT1
bosterbio.com/bosterbio-gene-info-cards/CHIT1
References
PMID: 7592832 by Boot R.G., et al. Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages.
PMID: 7836450 by Renkema G.H., et al. Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.