Chitinase-like protein 3 Antibodies

AND Chil3 ELISA kits, Chitinase-like protein 3 Proteins

Many biological assays use antibodies to detect Chitinase-like protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chitinase-like protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chitinase-like protein 3 antibodies...

We validate the specificity of these antibodies to Chitinase-like protein 3 by testing them on tissues known to express Chil3 positively and negatively. Browse below to find the Chil3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Chil3 Infographic by Boster Bio

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Mouse YM1/Chitinase 3-like 3/CHI3L3 ELISA Kit PicoKine®

6 Q&As

Mouse

ELISA

$750
Cat # EK2010
96 wells/kit, with removable strips.

Chil3 Overview

Facts about Chitinase-like protein 3.

Chil3 3D structure. Source: alphafold

Chitinase-like protein 3 (Chil3)

Lectin that contrasts saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much more powerful than binding to mono- or disaccharides.

Also binds chitin and heparin. Has weak hexosaminidase activity but no chitinase activity.

Gene Information

Mouse
Gene Name:	Chil3
Uniprot:	O35744
Entrez:	12655

Family

Belongs to:

glycosyl hydrolase 18 family

Alternative Names

AI505981; CHI3L3; Chitinase 3 like 3; Chitinase 3-like 3; ECF-L; YM1

Molecular Weight

Mass (kDA):
44.458 kDA

Genomic Context


Mouse

Location:	3 F2.2\|3 46.49 cM
Sequence:	3;

Tissue Specificity

Expressed in peritoneal cavity macrophages and in peritoneal and bone marrow-derived neutrophils. Abundantly expressed in bone marrow, with moderate levels detected in gastric antrum, spleen and in alveolar macrophages in lung. Not detected in brain, heart, liver, kidney, stomach, intestine, skeletal muscle, ovary, testis, thymus and lymph nodes (at protein level). Detected at low levels in bone marrow, spleen, thymus and lung. Barely detectable in intestine, kidney and coecum.

Diseases

Glioblastoma
Neoplasms
Glioblastoma Multiforme
Cerebral Amyloid Angiopathy
Amyloid Deposition
Glioma
Malignant Paraganglionic Neoplasm
Hypoxia
Crushing Injury
Brain Neoplasms
Degenerative Polyarthritis
Multiple Myeloma

Malignant Neoplasms
Low Grade Glioma
Innate Immune Response
Vascular Diseases
Senile Cerebral Amyloid Angiopathy
Senile Plaques
Alzheimer's Disease

Pathways

Cell Proliferation
Innate Immune Response
Proteolysis
Immune Response
Chondrocyte Differentiation

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Chil3

References

PMID: 9828134 by Jin H.M., et al. Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes.

PMID: 10625674 by Owhashi M., et al. Identification of a novel eosinophil chemotactic cytokine (ECF-L) as a chitinase family protein.