Chromogranin-A Antibodies

Chromogranin-A (CHGA)

Pancreastatin: Strongly inhibits glucose induced insulin release from the pancreas. .

Gene Information

Human
Gene Name:	CHGA
Uniprot:	P10645
Entrez:	1113

Family

Belongs to:
chromogranin/secretogranin protein family

Alternative Names

betagranin (N-terminal fragment of chromogranin A); Betagranin; Catestatin; CGA; CHGA; Chromofungin; chromogranin A (parathyroid secretory protein 1); Chromogranin A; chromogranin-A; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I

Molecular Weight

Mass (kDA):
50.688 kDA

Genomic Context

Human
Location:	14q32.12
Sequence:	14; NC_000014.9 (92922594..92935293)

Tissue Specificity

GE-25 is found in the brain.

Subcellular Localizations

[Serpinin]: Secreted. Cytoplasmic vesicle, secretory vesicle. Pyroglutaminated serpinin localizes to secretory vesicle.; Cytoplasmic vesicle, secretory vesicle. Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle. Secreted. Associated with the secretory granule membrane through direct interaction to SCG3 that in turn binds to cholesterol-enriched lipid rafts in intragranular conditions. In pituitary gonadotropes, located in large secretory granules.

Diseases

• Neoplasms
• Carcinoma
• Neuroendocrine Tumors
• Malignant Neoplasms
• Pheochromocytoma
• Carcinoid Tumor
• Hypertensive Disease
• Prostatic Neoplasms
• Malignant Neoplasm Of Prostate
• Pituitary Diseases
• Neoplasm Metastasis
• Lung Neoplasms
• Adenocarcinoma

• Pancreatic Neoplasm
• Adenoma
• Adrenal Gland Neoplasms
• Small Cell Carcinoma Of Lung
• Medullary Carcinoma Of Thyroid
• Hyperplasia
• Disease Of Adrenal Medulla

Pathways

• Secretion
• Localization
• Exocytosis
• Catecholamine Secretion
• Pathogenesis
• Secretory Pathway
• Hormone Secretion
• Regulated Secretory Pathway
• Cell Proliferation
• Proteolysis
• Glomerular Filtration
• Cell Differentiation
• Excretion

• Acid Secretion
• Cell Adhesion
• Insulin Secretion
• Glycosylation
• Transport
• Translation
• Cell Growth

PTMs

• Cleavage
• Phosphorylation
• Glycosylation
• Amidation
• Methylation

• Sulphation
• Nitrosylation
• Deamination
• Oxidation
• Deglycosylation

Research Areas

• Cancer
• Neuronal Cell Markers
• Tumor Biomarkers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHGA

Best Uses Of The CHGA Marker

If you're seeking an antibody against the CHGA marker the Boster Bio CHGA Antibody Picoband may be able to help. The product is available in a variety of formats that can be used for different applications. Boster's unique process involves testing antibodies against positive and negative samples in order to ensure high specificity and high affinity. The Boster Bio CHGA-Antibody picoband can be useful for a variety of purposes, ranging from basic research to clinical trials.

Boster Bio Anti Glycophorin A/CD235a (Erythrocyte marker)

Anti-GlycophorinA and CD235a antibodies are monoclonal mouse antigens to the glycophorins B and A of the cell membrane of the erythrocyte. Both antibodies contain antigenic determinants of MN and Ss blood groups. They are closely related and include all variant phenotypes that belong to the Miltenberger complex.

The antigen is highly specific and efficient to detect glycophorins A and B. The antigens were detected on erythrocyte microparticles with flow cytometry. These antibodies were found recognize glycophorins A and in both blood group antigens. They were also recognized by blood group antigens, Leb, LU1, and MNS3.

Boster Bio has been manufacturing antibodies since 1993, and specializes in picogram sensitivities ELISA kits and IHC-optimized polyclonal antibody. The antibody line includes more than 12,000 antibodies that are each validated for IHC and WB, Flow and ELISA. Each antibody has been rigorously tested and validated on untransfected cells.

If you are interested in purchasing Boster Bio Anti-Glycophorin A / CD235a antibody, please contact Sanbio. They can answer any questions you have, provide BeNeLux delivery, and even customize the product for your research. Don't delay! Get the latest Boster Bio Anti-Glycophorin A CD235a (Erythrocyte Marker) antibody today!

This antibody is a suitable candidate for detection of apoptotic cell and platelets. It inhibits the activation of platelets and reduces tumor growth and metastasis in the vivo. These antibodies can also be used to detect blood-borne viruses. However, the results are only used to test for the presence of this protein in small amounts.

Microparticles that originate from monocytes or THP-1 cells possess a different procoagulant function than those derived from platelets or endothelial cell. This may be due to the active tissue factor. Anti-Glycophorin A/CD235a (Erythrocyte Marker) antibody has higher affinity for platelets as well as granulocytes.

This antibody is able to be used in a wide range of uses and is compatible with platelet concentrates. It decreases the number of NK cells and increases human CD34ao cells. Furthermore, it boosts the immune response of erythrocytes as well as NK cells. It has a high safety profile and is recommended for use in various clinical studies.

Boster Bio Anti-PROM1 Antibody Picoband

Boster Bio Anti-PROM1 Antibody Picoband was validated by using negative and positive samples of ELISA and IHC-P. This antibody reacts with Rats and Mouse. You can purchase the blocking peptide on its own for a year. Boster offers product credits to the first reviewer who reviews the product. Scientists from all over the world can receive this incentive.

Boster Bio Anti-PROM1 Antibody

Boster Bio Anti PROM1 Anti-Bax Monoclonal antibody reacts to Human, Mouse, and Rat. This product has been tested on a variety of tests and has been confirmed by Boster Bio scientists. The antibody is stored at 4°C for a month. It is made up of 5 mg of BSA and peptides. The blocking peptide is sold separately and varies in cost dependent on the length of the immunogen.