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Liver carboxylesterase 1 Antibodies
AND CES1 ELISA kits, Liver carboxylesterase 1 Proteins
Many biological assays use antibodies to detect Liver carboxylesterase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Liver carboxylesterase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Liver carboxylesterase 1 antibodies...
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CES1 Infographic by Boster Bio
All CES1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01741-1
100 μg/vial
Cat # A01741-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, WB
$370
Cat # M01741
100 μl
Cat # M01741
100 μl
Human CES1 ELISA Kit PicoKine®
10 Q&As
Human
ELISA
$499
Cat # EK1813
96 wells/kit, with removable strips.
Cat # EK1813
96 wells/kit, with removable strips.
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01741-1
100 μg/vial
Cat # M01741-1
100 μg/vial
Enzyme Activity, SDS-PAGE
$293
Cat # PROTQ8VCC2
Starting from 10ug
Cat # PROTQ8VCC2
Starting from 10ug
Human
ELISA
$499
Cat # FEK1813
96 wells/kit, with removable strips.
Cat # FEK1813
96 wells/kit, with removable strips.
Human
$628
Cat # LS001066
100 µg
Cat # LS001066
100 µg
CES1 Overview
Facts about Liver carboxylesterase 1.
Liver carboxylesterase 1 (CES1)
Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester.
Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene.
Gene Information
| Human | |
|---|---|
| Gene Name: | CES1 |
| Uniprot: | P23141 |
| Entrez: | 1066 |
Family
| Belongs to: |
|---|
| type-B carboxylesterase/lipase family |
Alternative Names
ACAT; acyl coenzyme A:cholesterol acyltransferase; Acyl-coenzyme A:cholesterol acyltransferase; Brain carboxylesterase hBr1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); Carboxylesterase 1; carboxylesterase 2 (liver); CEH; CES1; Ces-1; CES1A2; CES2EC 3.1.1.1; cholesteryl ester hydrolase; Cocaine carboxylesterase; EC 3.1.1; Egasyn; HMSE1; HMSECES1A1; human monocyte/macrophage serine esterase 1; liver carboxylesterase 1; MGC117365; Monocyte/macrophage serine esterase; PCE-1; REH; Retinyl ester hydrolase; Serine esterase 1; SES1; Ses-1; SES1TGH; TGH; Triacylglycerol hydrolase
Molecular Weight
Mass (kDA):
62.521 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16q12.2 |
| Sequence: | 16; NC_000016.10 (55802851..55833127, complement) |
Tissue Specificity
Expressed predominantly in liver with lower levels in heart and lung.
Subcellular Localizations
Endoplasmic reticulum lumen.
Diseases
- Malignant Neoplasms
- Neoplasms
- Obesity
- Atherosclerosis
- Liver Carcinoma
- Liver Diseases
- Cholangiocarcinoma
- Influenza
- Hepatitis
- Insulin Resistance
- Hepatotoxicity
- Steatohepatitis
- Steatosis
Pathways
- Transport
- Secretion
- Intestinal Absorption
- Cell Growth
- Sensitization
- Translation
- Cholesterol Transport
- Methylation
- Reverse Cholesterol Transport
- Cell Activation
- Cytokine Secretion
- Reverse Transcription
- Cell Differentiation
PTMs
- Oxidation
- Carboxylation
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CES1
bosterbio.com/bosterbio-gene-info-cards/CES1
References
PMID: 1918003 by Munger J.S., et al. A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases.
PMID: 8218228 by Kroetz D.L., et al. Glycosylation-dependent activity of baculovirus-expressed human liver carboxylesterases: cDNA cloning and characterization of two highly similar enzyme forms.