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CEP250 Antibodies
AND CEP250 ELISA kits, CEP250 Proteins
Many biological assays use antibodies to detect CEP250, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CEP250 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CEP250 antibodies...
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CEP250 Infographic by Boster Bio
All CEP250 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A07150-1
100 μg/vial
Cat # A07150-1
100 μg/vial
CEP250 Overview
Facts about Centrosome-associated protein CEP250.
Centrosome-associated protein CEP250 (CEP250)
Probably plays an significant role in centrosome cohesion during interphase. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CEP250 |
| Uniprot: | Q9BV73 |
| Entrez: | 11190 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
250-KD; centrosomal Nek2-associated protein 1,250 kDa centrosomal protein; centrosomal protein 250kDa; centrosome associated protein; centrosome-associated protein CEP250; CEP2; CNAP1; C-NAP1; MGC88542
Molecular Weight
Mass (kDA):
281.137 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q11.22 |
| Sequence: | 20; NC_000020.11 (35455137..35519280) |
Tissue Specificity
Ubiquitously and weakly expressed.
Subcellular Localizations
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Component of the core centrosome. In interphase cells, it specifically associates with the proximal ends of both mother and daughter centrioles. Associates with the centrosome in interphase cells. In mitotic cells, it dissociates from the mitotic spindle poles. At the end of cell division, it r
Diseases
- Malignant Neoplasms
- Anaplastic Large Cell Lymphoma, Alk-positive
- Peripheral T-cell Lymphoma
- Ki-1+ Anaplastic Large Cell Lymphoma
- Malignant Tumor Of Colon
- B-cell Lymphomas
- Adult Non-hodgkin Lymphoma
- Autoimmune Diseases
- Autoimmune Reaction
- Neoplasms
Interacting Proteins
- Axin2
- SIK2
Pathways
- Mitosis
- Cell Cycle
- Interphase
- Cell Division
- S Phase
- Proteolysis
- Metaphase
- M Phase
- Chromosome Segregation
- Localization
- Cytokinesis
PTMs
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CEP250
bosterbio.com/bosterbio-gene-info-cards/CEP250
References
PMID: 9506584 by Mack G.J., et al. Autoantibodies to a group of centrosomal proteins in human autoimmune sera reactive with the centrosome.
PMID: 9647649 by Fry A.M., et al. C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.