This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
, No Gclids
Ccr2 Antibodies
AND Ccr2 ELISA kits, Ccr2 Proteins
Many biological assays use antibodies to detect Ccr2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ccr2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ccr2 antibodies...
Previous: SEPTIN9
Next: Ccr8
Ccr2 Infographic by Boster Bio
All Ccr2 Products
Product
Figures
Specificity
Applications
Price
Anti-CCR2/CKR2 Rabbit Monoclonal Antibody
2 Citations 15 Q&As
Human, Mouse
Flow Cytometry, IP, IHC, WB
$370
Cat # M00158
100 μl
Cat # M00158
100 μl
Anti-CCR2 Antibody Picoband®
1 Citations 16 Q&As
Human, Mouse, Rat
ELISA, WB
$370
Cat # A00158-4
100 μg/vial
Cat # A00158-4
100 μg/vial
Human
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00158-1
100 μg/vial
Cat # M00158-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IHC, WB
$405
Cat # A00158
100ul
Cat # A00158
100ul
Ccr2 Overview
Facts about C-C chemokine receptor type 2.
C-C chemokine receptor type 2 (Ccr2)
Receptor for the CCL2, CCL7 and CCL12 chemokines (PubMed:8996246).
Receptor for the beta-defensin DEFB106A/DEFB106B (By similarity).Transduces a signal by increasing intracellular calcium ion levels (PubMed:8996246). Upon CCL2 ligation, mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Ccr2 |
| Uniprot: | P51683 |
| Entrez: | 12772 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CC-CKR-2CKR2B; CCR2; CCR-2; CCR2A; CCR2B; CD192 antigen; CD192; chemokine (C-C motif) receptor 2; CKR2; CKR2A; CMKBR2; CMKBR2MGC111760; FLJ78302; MCP-1 receptor; MCP-1-R; MCP-1-RMGC103828; MGC168006; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor
Molecular Weight
Mass (kDA):
42.783 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 9 F4|9 75.05 cM |
| Sequence: | 9; |
Tissue Specificity
Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines.
Diseases
- Inflammation
- Cholangiocarcinoma
- Hiv Infections
- Atherosclerosis
- Immunologic Deficiency Syndromes
- Acquired Immunodeficiency Syndrome
- Autoimmune Reaction
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Fibrosis
- Inflammatory Response
Pathways
- Chemotaxis
- Pathogenesis
- Immune Response
- Secretion
- Cell Migration
- Inflammatory Response
- Angiogenesis
- Localization
- Monocyte Chemotaxis
- Cell Proliferation
- Leukocyte Migration
- Regeneration
- Hypersensitivity
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Biotinylation
- Reduction
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ccr2
bosterbio.com/bosterbio-gene-info-cards/Ccr2
References
PMID: 8631787 by Boring L., et al. Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9.
PMID: 8662823 by Kurihara T., et al. Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC.
2 Publications of Boster Ccr2 Antibodies & ELISA Kits
- PubMed ID: 26648448, N%u2011methyl%u2011N%u2011nitro%u2011N'%u2011nitrosoguanidine induces the expres...
- PubMed ID: 24416340, Zhao C, Bu X, Wang W, Ma T, Ma H. Plos One. 2014 Jan 8;9(1):E85058. Doi: 10.1371...
*More publications can be found for each product on its corresponding product page